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| http://dx.doi.org/10.1136/bcr-2018-224827 | DOI Listing |
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Deciphering the COVID-19 density puzzle: A meta-analysis approach.
Soc Sci Med
December 2024
School of Economics, University of Hyderabad, Gachibowli, Hyderabad, Telangana, 500046, India. Electronic address:
The COVID-19 pandemic has sparked widespread efforts to mitigate its transmission, raising questions about the role of urban density in the spread of the virus. Understanding how city density affects the severity of communicable diseases like COVID-19 is crucial for designing sustainable, pandemic-resilient cities. However, recent studies on this issue have yielded inconsistent and conflicting results.
View Article and Find Full Text PDFPerceptions of Pharmacy Educators Regarding the NAPLEX Pass Rate Puzzle.
Am J Pharm Educ
December 2024
University of Kentucky College of Pharmacy, USA; American Journal of Pharmaceutical Education, USA.
Objective: Identify perceptions from pharmacy faculty across the Academy concerning factors that may be influencing North American Pharmacist Licensure Examination (NAPLEX) first-time pass rates to highlight potential focused areas of further research based on common experiences.
Methods: An anonymous 43-item Qualtrics questionnaire was distributed to faculty members from the American Association of Colleges of Pharmacy. Questions were predominantly 5-point Likert scale items (5 = very large impact) and encompassed 6 domains: pharmacy school factors, COVID-19 educational modifications, testing factors, standardized testing, applicant preparedness, and student factors.
Differential patterns of antibody response against SARS-CoV-2 nucleocapsid epitopes detected in sera from patients in the acute phase of COVID-19, convalescents, and pre-pandemic individuals.
Pathog Dis
February 2024
Department of Microbiology, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, ul. Rudolfa Weigla 12, 53-114 Wrocław, Poland.
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has already infected more than 0.7 billion people and caused over 7 million deaths worldwide. At the same time, our knowledge about this virus is still incipient.
View Article and Find Full Text PDFAlphaFold2 Reveals Structural Patterns of Seasonal Haplotype Diversification in SARS-CoV-2 Nucleocapsid Protein Variants.
Viruses
August 2024
Evolutionary Bioinformatics Laboratory, Department of Crop Sciences, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
The COVID-19 pandemic saw the emergence of various Variants of Concern (VOCs) that took the world by storm, often replacing the ones that preceded them. The characteristic mutant constellations of these VOCs increased viral transmissibility and infectivity. Their origin and evolution remain puzzling.
View Article and Find Full Text PDFCOVID-19 thromboinflammation: adding inflammatory fibrin to the puzzle.
Trends Immunol
October 2024
IRCCS Humanitas Research Hospital, Rozzano (Milan), Italy; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele (Milan), Italy. Electronic address:
Thromboinflammation is a peculiar and key component of acute COVID-19 pathogenesis, which contributes to long COVID. In a recent study, Ryu et al. demonstrate that the SARS-CoV-2 spike protein interacts with fibrinogen, promoting fibrin polymerization and its inflammatory activity.
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