A new alkaloid, (10, 12)-9-ureidooctadeca-10, 12-dienoic acid, named oleraurea and 10 known compounds, -hydroxybenzaldehyde , -hydroxybenzoic acid , -hydroxyacetophenone , benzamide , (--coumaramide , ()-ferulamide , soyalkaloid A , -carboline-3-carboxylic acid , 2, 3, 4, 9-tetrahydro--pyrido [3, 4-] indole-3-carboxylic acid , (1, 3)-1-methyl-1, 2, 3, 4-tetrahydro--carboline-3-carboxylic acid were obtained from L., in which, compounds , , were isolated from the plant for the first time. The structure of the compound was identified using spectroscopic methods including 1D and 2D NMR, HR-ESI-TOF-MS. The compounds presented anticholinesterase activities, but the extract (POE) presented very low anticholinesterase activity.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1080/14786419.2018.1460833 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Effect of Dietary Supplementation of Red and Larch Pine Needle Powders on Productivity, Egg Quality, Yolk Fatty Acids and Cholesterol and Hatchability of Laying Quails.
J Anim Physiol Anim Nutr (Berl)
January 2025
Faculty of Agriculture Department of Animal Science, Sehit Bülent Yurtseven Kampüsü, Igdır University, Igdir, Turkey.
This study aimed to determine the efficacy of red pine and larch pine needles powder at different doses on productive performance, egg quality, hatching parameters, total fatty acid and cholesterol levels of laying quails. A total of 126 (84 ♀ and 42 ♂) 20-week-old laying quail were randomly distributed into seven experimental diets with three replicates of six (four female and two male) birds per cage. The groups were fed a basal diet (CON group), a basal diet with red pine needle powder (RPNP group) (1.
View Article and Find Full Text PDFLactate accumulation promotes immunosuppression and fibrotic transformation of bone marrow microenvironment in myelofibrosis.
J Transl Med
January 2025
Department of Biomedical and Biotechnological Sciences, Division of Medical Biochemistry, University of Catania, Catania, Italy.
Background: Clonal myeloproliferation and fibrotic transformation of the bone marrow (BM) are the pathogenetic events most commonly occurring in myelofibrosis (MF). There is great evidence indicating that tumor microenvironment is characterized by high lactate levels, acting not only as an energetic source, but also as a signaling molecule.
Methods: To test the involvement of lactate in MF milieu transformation, we measured its levels in MF patients' sera, eventually finding a massive accumulation of this metabolite, which we showed to promote the expansion of immunosuppressive subsets.
Protein palmitoylation is involved in regulating mouse sperm motility via the signals of calcium, protein tyrosine phosphorylation and reactive oxygen species.
Biol Res
January 2025
School of Pharmacy, Hangzhou Medical College, Hangzhou, Zhejiang, China.
Background: Protein palmitoylation, a critical posttranslational modification, plays an indispensable role in various cellular processes, including the regulation of protein stability, mediation of membrane fusion, facilitation of intracellular protein trafficking, and participation in cellular signaling pathways. It is also implicated in the pathogenesis of diseases, such as cancer, neurological disorders, inflammation, metabolic disorders, infections, and neurodegenerative diseases. However, its regulatory effects on sperm physiology, particularly motility, remain unclear.
View Article and Find Full Text PDFProtective effects of Notoginsenoside R2 on reducing lipid accumulation and mitochondrial dysfunction in diabetic nephropathy through regulation of c-Src.
Chin Med
January 2025
Department of Nephrology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Background: The treatment options to delay the progression of diabetic nephropathy (DN), a key contributor to chronic kidney disease (CKD), are urgently needed. Previous studies reported that traditional Chinese medicine Panax notoginseng (PNG) exerted beneficial effects on DN. However, the renoprotective effects of Notoginsenoside R2 (NR2), an active component of PNG, on DN have not been investigated.
View Article and Find Full Text PDFPhosphorylation of Bok at Ser-8 blocks its ability to suppress IPR-mediated calcium mobilization.
Cell Commun Signal
January 2025
Department of Pharmacology, SUNY Upstate Medical University, Syracuse, NY, 13210, USA.
Background: Bok is a poorly characterized Bcl-2 protein family member with roles yet to be clearly defined. It is clear, however, that Bok binds strongly to inositol 1,4,5-trisphosphate (IP) receptors (IPRs), which govern the mobilization of Ca from the endoplasmic reticulum, a signaling pathway required for many cellular processes. Also known is that Bok has a highly conserved phosphorylation site for cAMP-dependent protein kinase at serine-8 (Ser-8).
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!