: To analyze the peak expiratory flow (PEF) in obese subjects in standing (ST), seated (SE), supine (SU), prone (PR), and right and left lateral decubitus (RL and LL) positions. : 36 obese volunteers, aged between 18 and 54 years, and nonsmokers, were evaluated by anthropometric data; spirometry; international physical activity questionnaire (IPAQ); and PEF in ST, SE, SU, PR, RL, and LL positions, randomly. : The mean age was 27.3 ± 7.4 years and BMI of 38.7 ± 3.2 kg/m; IPAQ results: active (50%), irregularly active (25%), very active (16.7%), and sedentary (08.3%); spirometry results: FVC = 100.33%, FEV = 92.83%, FEV/FVC ratio = 0.95, FEF = 85.55%. The PEF (L/min) were within the normal range and there was no difference between the ST and SE (428.6 ± 100.9 and 430.0 ± 100.1). Comparing ST and SE to the other positions, in absolute and percent of predicted values (L/min and %), there was a decrease in the SU (85.4 ± 14.9), PR (401.1 ± 92.4 and 84.1 ± 14.4), RL (398.6 ± 94.7 and 83.3 ± 14.9) ( < 0.05), and there was no difference to SU (409.4 ± 102.8) and LL (410.3 ± 93.9 and 85.8 ± 14.5). : The PEF of healthy obese are similar in the standing and seated positions. The PEF decreases in the lying positions, except for the LL, that could be used as an alternative for measurements.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1080/09593985.2018.1461286 | DOI Listing |
Biomed Pharmacother
January 2025
Department of Pediatrics, Case Western Reserve University, Cleveland, OH, USA; Department of Pharmacology, Case Western Reserve University, Cleveland, OH 44106, USA.
An understanding of intracellular mechanisms by which fentanyl and other synthetic opioids exert adverse effects on breathing is needed. Using freely moving adult male guinea pigs, we administered the nitric oxide synthase (NOS) inhibitor, L-NAME (N-nitro-L-arginine methyl ester), to determine whether nitrosyl factors, such as nitric oxide and S-nitrosothiols, play a role in fentanyl-induced respiratory depression. Ventilatory parameters were recorded by whole body plethysmography to determine the effects of fentanyl (75 μg/kg, IV) in guinea pigs that had received a prior injection of vehicle (saline), L-NAME or the inactive D-isomer, D-NAME (both at 50 μmol/kg, IV), 15 min beforehand.
View Article and Find Full Text PDFToxicol Ind Health
January 2025
Department of Respiratory Diseases, Zhejiang Hospital, Hangzhou, China.
Perfluoroalkyl chemicals are one of the most stable substances in industry and have become ubiquitous contaminants owing to their persistence in the environment. This study enrolled 1,953 participants aged ≥40 years old using data from the National Health and Nutrition Examination Survey (NHANES). We selected four perfluoroalkyl chemicals with a detection frequency of more than 80%, including perfluorohexane sulfonic acid (PFHxS), perfluorononanoic acid (PFNA), perfluorooctanoic acid (PFOA), and perfluorooctane sulfonic acid (PFOS).
View Article and Find Full Text PDFZhongguo Gu Shang
January 2025
Department of Thoracic Surgery, Hanyang Hospital, Wuhan University of Science and Technology, Wuhan 430050, Hubei, China.
Objective: To investigate the clinical efficacy of thoracoscopic minimally invasive surgery with nickel-titanium shape memory alloy wrap bone plate versus rib periosteal internal fixation in patients with multiple rib fractures (MRF) and flail chest.
Methods: A retrospective analysis was performed on 100 patients with MRF and flail chest treated with thoracoscopic minimally invasive surgery and internal fixation with rib fracture preservation between January 2019 and December 2022, including 54 males and 46 females, aged from 20 to 65 years old, with an average age of (38.0±18.
JAMA Otolaryngol Head Neck Surg
January 2025
Department of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, Tennessee.
Importance: Airway stenosis is a rare but debilitating disorder that significantly degrades the quality of life in affected patients. Treatments are primarily surgical, and disease management lacks established medical therapies. The North American Airway Collaborative held its third symposium at The Johns Hopkins Hospital in Baltimore, Maryland, on April 15, 2024, focused on strategies to advance the care of these patients.
View Article and Find Full Text PDFSurg Endosc
January 2025
Department of Anesthesiology and Reanimation, Faculty of Medicine, Istınye University Medicalpark Gaziosmanpasa Hospital, Istanbul, Turkey.
Background: The aim of our study is to compare the effect of the 30° reverse Trendelenburg position combined with the beach chair position on respiratory parameters in laparoscopic sleeve gastrectomy (LSG) with the 30° reverse Trendelenburg position alone.
Material And Method: Fifty patients with body mass index > 30 were included in the study. The patients were divided into two groups; in the control group, the standard 30° reverse Trendelenburg.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!