Stable and oxidant responsive zwitterionic nanoclusters.

Nanoscale

Department of Chemistry, University of Massachusetts-Amherst, 710 North Pleasant Street, Amherst, Massachusetts 01003, USA.

Published: April 2018

Zwitterions are promising ligands for the fabrication of non-toxic and non-interacting biomaterials. Sulfonamide-based monothiol zwitterionic ligands on gold nanocluster (AuNC) surfaces provide nanomaterials with stable colloidal properties and intense red emission in biological environments. The fluorescence intensity of the nanocluster can be modulated by reactive oxygen species (e.g. ˙OH), allowing for quantitative and selective sensing of antioxidants (e.g. ascorbic acid) in real time.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397623PMC
http://dx.doi.org/10.1039/c7nr08951aDOI Listing

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