AI Article Synopsis
- A 44-year-old man with recurrent retroperitoneal liposarcoma was treated with pazopanib.
- After 15 months on the medication, a CT scan revealed intestinal edema, but he showed no symptoms.
- An endoscopy found marked swelling in the intestine, and pathology indicated crystal deposition and fat accumulation, which completely resolved after stopping pazopanib.
Article Abstract
Pazopanib was administered to a 44-year-old man with local recurrence of retroperitoneal liposarcoma. Computed tomography showed an intestinal edema, which gradually progressed 15 months after pazopanib administration although he had no clinical symptoms. Upper gastrointestinal endoscopy implicated marked edematous hypertrophy of the Kerkling's fold. Pathological findings showed crystal deposition and fat accumulation, without a malignant component. All these abnormal findings resolved after pazopanib discontinuation.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/iju.13567 | DOI Listing |
Publication Analysis
Top Keywords
crystal deposition
8
retroperitoneal liposarcoma
8
pazopanib-induced crystal
4
deposition intestinal
4
intestinal mucosa
4
mucosa patient
4
patient retroperitoneal
4
liposarcoma pazopanib
4
pazopanib administered
4
administered 44-year-old
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!