Background: Large numbers of population suffer from burn annually. The promising treatment of burn has not been identified yet. () in family is popular for its antiseptic activity. This prospective study was designed to compare the wound healing effects of gel (AG) with silver sulfadiazine (SSD).
Methods: This single blind clinical trial was performed on 40 patients with second and third degree burns. 20 patients treated with SSD and 20 other patients received . The percentage of the wound healing was evaluated with pain, irritation, edema, itching, erythema, purulent discharges and skin discoloration symptoms. Also, the patients' satisfaction and adverse drug reactions were determined.
Results: The severity of pain (=0.03), inflammation (=0.02) and purulent secretions (=0.03) were significantly relieved in group. The healing time significantly reduced in second degree burns (=0.03) and third degree burns (=0.04) with treating by . No significant adverse drug reactions were detected with .
Conclusion: It seems that improves the different therapeutic aspects of burn injuries and could be considered as a new herbal remedy in wound healings.
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JMIR Med Inform
January 2025
Department of Systems Design Engineering, Faculty of Engineering, University of Waterloo, Waterloo, ON, Canada.
Background: While expert optometrists tend to rely on a deep understanding of the disease and intuitive pattern recognition, those with less experience may depend more on extensive data, comparisons, and external guidance. Understanding these variations is important for developing artificial intelligence (AI) systems that can effectively support optometrists with varying degrees of experience and minimize decision inconsistencies.
Objective: The main objective of this study is to identify and analyze the variations in diagnostic decision-making approaches between novice and expert optometrists.
Burns
January 2025
Department of Burns and Wound Center, Second Affiliated Hospital, College of Medicine, Zhejiang University, Hang Zhou 310009, PR China. Electronic address:
Background: On June 13, 2020, an explosion involving a liquefied natural gas (LNG) tanker truck occurred in eastern China. Fifteen patients with extremely severe burns (referred to as "June 13" patients) were treated in the burn-intensive care unit (ICU) joint ward within the general ICU.
Methods: A multidisciplinary treatment team comprising 129 doctors, 126 nurses, and 165 auxiliary staff members was assembled.
J Oral Rehabil
January 2025
Universidade Federal de São Paulo-Escola Paulista de Medicina-UNIFESP-EPM, São Paulo, Brazil.
Objective: The objective of this research is to evaluate the effectiveness and safety of photobiomodulation or low-level laser therapy on burning mouth syndrome compared to placebo, no-laser, clonazepam and alpha-lipoic acid.
Methods: A systematic review of randomised clinical trials was performed. The databases consulted were MEDLINE, CENTRAL, LILACS, EMBASE and clinical trial registries ClincalTrial.
Int J Biol Macromol
January 2025
The Collaborative Innovation Center for Eco-Friendly and Fire-Safety Polymeric Materials (MoE), College of Chemistry, Sichuan University, Chengdu 610064, China.
The development of bio-based flame retardants has garnered significant attention, however, significant challenges remain in achieving efficient flame retardancy and eco-friendly preparation methods. Herein, we propose a facile, atomic-efficient, and eco-friendly strategy for synthesizing a trinity chitosan-based flame retardant, phosphite-protonated chitosan (PCS). The chemical structure was systematically analyzed and the impact of varying degrees of protonation on the dissolution behavior and rheological properties were investigated.
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January 2025
Department of Burn and Plastic Surgery, Affiliated Hospital of Nantong University, Nantong, 226001, China.
Hepatocyte growth factor (HGF) is a substance that stimulates the proliferation of hepatocytes which promote healing. We developed a macrophage membrane-encapsulated nanosphere drug delivery system containing HGF for the study of burn wound healing. Twenty-seven Sprague-Dawley rats were randomly divided into three groups: a saline control (NS) group, an engineered macrophage membrane-encapsulated nanospheres (ETMM@NPS) group, and an engineered macrophage membrane-encapsulated nanospheres treatment with HGF-loaded gene (HGF@ETMM@NPS) group.
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