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Beyond templates: exploring uncharted territory in anisotropic gold nanostructure-oligomer composites synthesis and electrocatalytic performance towards environmental pollutants.
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Department of Physics, Faculty of Science, Kasetsart University Bangkok 10900 Thailand
The synthesis of polymer/oligomer-stabilized metal nanostructures (MNS) opens up a wide range of possibilities, from fundamental materials science to practical applications in domains such as medicine, catalysis, sensing, and energy. Because of the versatility of this synthetic approach, it is a dynamic and ever-changing field of study. These polymers/oligomers have precise control over the nucleation and growth kinetics, allowing the production of mono-disperse MNS with well-defined properties.
View Article and Find Full Text PDFA review of precision medicine in developing pharmaceutical products: Perspectives and opportunities.
Int J Pharm
December 2024
Pharmacogenomics (PGx) Laboratory, University of Puerto Rico, Medical Sciences Campus, San Juan, PR, 00936, United States; Department of Pharmaceutical Sciences, School of Pharmacy, University of Puerto Rico - Medical Sciences Campus, San Juan, PR 00936, United States. Electronic address:
Over the next decade, Precision Medicine (PM) is poised to become the standard of care in pharmaceutical therapy, necessitating a fundamental transformation in the design and development of innovative custom-made drug products. To date, a comprehensive review linking PM with practical personalized drug formulations is missing. This review attempts to provide an overview of state-of-the-art formulation approaches capable of translating PM evaluation and resulting recommendations (clinical research) into tailored drug products (non-clinical research) for real-world patients.
View Article and Find Full Text PDFAthRiboNC: an Arabidopsis database for ncRNAs with coding potential revealed from ribosome profiling.
Database (Oxford)
December 2024
Department of Bioinformatics, College of Life Sciences, Zhejiang University, Hangzhou 310058, China.
Non-coding RNAs (ncRNAs) are traditionally considered incapable of encoding proteins, but new evidence suggests that small open reading frames (sORFs) within ncRNAs can actually encode biologically functional small peptides. Despite growing recognition of their importance, a systematic exploration of plant ncRNAs with coding potential has remained largely uncharted territory, especially in the context of their translational activities. By collecting and analyzing Ribo-Seq data from 226 Arabidopsis thaliana samples, we have integrated extensive information on Arabidopsis ncRNAs with coding potential and developed the AthRiboNC database, a novel and dedicated database that consolidates extensive information on ncRNAs with coding potential in Arabidopsis.
View Article and Find Full Text PDFPre- and Post-Exposure Prophylaxis in Sexually Transmitted Diseases: An Uncharted Territory.
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From the Department of Dermatology, Venereology and Leprosy, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India E-mail:
Structural Insight on the Selectivity of Calyx[4]Arene-Based Inhibitors of MgDependent Atp-Hydrolases.
Mol Inform
December 2024
Palladin Institute of Biochemistry NAS of Ukraine, 9 Leontovich str., Kyiv, 01054, Ukraine.
Located in plasma membranes, ATP hydrolases are involved in several dynamic transport processes, helping to control the movement of ions across cell membranes. ATP hydrolase acts as a transport protein, converting energy from ATP hydrolysis into transport molecules against their concentration gradients. In addition to energy metabolism and active transport, ATP hydrolase is essential for maintaining cellular homeostasis and cell function.
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