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Corynebacterium pseudotuberculosis: Whole genome sequencing reveals unforeseen and relevant genetic diversity in this pathogen.
PLoS One
August 2024
Chemical and Veterinary Analysis Agency Stuttgart, Fellbach, Germany.
Corynebacterium pseudotuberculosis (CPS) is an important bacterial animal pathogen. CPS causes chronic, debilitating and currently incurable infectious diseases affecting a wide range of livestock and wild herbivores including camelids worldwide. Belonging to the Corynebacterium diphtheriae complex, this pathogen can also infect humans.
View Article and Find Full Text PDFMolecular basis for sortase-catalyzed pilus tip assembly.
mBio
September 2024
Division of Oral & Systemic Health Sciences, School of Dentistry, University of California, Los Angeles, California, USA.
Unlabelled: During pilus assembly within the Gram-positive bacterial envelope, membrane-bound sortase enzymes sequentially crosslink specific pilus protein monomers through their cell wall sorting signals (CWSS), starting with a designated tip pilin, followed by the shaft made of another pilin, ultimately anchoring the fiber base pilin to the cell wall. To date, the molecular determinants that govern pilus tip assembly and the underlying mechanism remain unknown. Here, we addressed this in the model organism .
View Article and Find Full Text PDFAdhesive Capsulitis Following Improper Tetanus-Diphtheria (Td) Booster Administration.
Cureus
March 2024
Physical Medicine and Rehabilitation, University of Pennsylvania, Philadelphia, USA.
Adhesive capsulitis following vaccination is a rare complication secondary to improper intramuscular (IM) deltoid vaccine administration. It is considered a subset of the broad category known as shoulder injury related to vaccine administration (SIRVA). SIRVA typically results from improper shoulder anatomic localization prior to injection, leading to erroneous placement of the needle into the glenohumeral joint capsule or subacromial space.
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