This is a review article. Eclampsia is an almost preventable condition. The ratio of prostacycline and thromboxane is reversed in patients with preeclampsia and eclampsia. Lipid peroxides are also increased during pregnancy and there is lack of invasion of the spiral arteries by trophoblasts, particularly the second wave. A good predictive test is urgently needed to detect patients who are at risk of developing these conditions later in their pregnancy. Low-dose aspirin is a promising preventive therapy in this group of women. Until we have good means of preventing preeclampsia and eclampsia, supportive care in treatment must be improved. Essential obstetric care (EOC) at all levels of health services should be established to reduce maternal mortality and morbidity from this condition, and the community educated and mobilized to respond appropriately in time of need.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/0020-7292(95)02489-Y | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Severe Maternal Morbidity Associated With Chronic Hypertension, Preeclampsia, and Gestational Hypertension.
JAMA Netw Open
January 2025
Magee-Womens Research Institute, Department of Obstetrics, Gynecology and Reproductive Sciences, Epidemiology and Clinical and Translational Research, University of Pittsburgh, Pittsburgh, Pennsylvania.
Importance: Chronic hypertension and preeclampsia are leading risk enhancers for maternal-neonatal morbidity and mortality. Severe maternal morbidity (SMM) indicators include heart, kidney, and liver disease, but studies have not excluded patients with preexisting diseases that define SMM. Thus, SMM risks for uncomplicated chronic hypertension specific to preeclampsia remain unclear.
View Article and Find Full Text PDFEvaluating the ability of fullPIERS calculator to predict adverse maternal outcomes in pre-eclampsia at Charlotte Maxeke Johannesburg Academic Hospital.
Int J Gynaecol Obstet
January 2025
Obstetrics and Gynaecology Department, Charlotte Maxeke Johannesburg Academic Hospital, University of the Witwatersrand, Johannesburg, South Africa.
Objective: To evaluate the ability of the fullPIERS model to predict adverse maternal outcomes in patients diagnosed as early-onset pre-eclampsia at Charlotte Maxeke Johannesburg Academic Hospital, South Africa.
Methods: Retrospective record review and analysis of 134 patients admitted with early-onset pre-eclampsia. Demographic data, symptoms, and investigation results relevant to the fullPIERS calculator present on admission were collected.
Evaluation of placental growth factor, Vitamin D, and systemic inflammatory index as predictive biomarkers for preeclampsia severity: a retrospective cohort study.
BMC Pregnancy Childbirth
January 2025
Department of Gynecology and Obstetrics, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, China.
Aim: Our study aimed to evaluate the predictive value of Placental growth factor (PlGF), Vitamin D, and systemic inflammatory index for assessing preeclampsia risk and severity.
Materials And Methods: This retrospective cohort study included 457 pregnant individuals who delivered at our hospital between March 2023 and October 2024. Participants were divided into three groups: control (n = 217), mild preeclampsia (n = 101), and severe preeclampsia (n = 67).
Retrospective evaluation of patients admitted to the intensive care unit due to obstetric reasons in terms of maternal near-miss, a five-year case-control study.
BMC Pregnancy Childbirth
January 2025
İzmir Bozyaka Training and Research Hospital, Department of Family Medicine, Health Sciences University, İzmir, Turkey.
Background: Maternal Near-Miss (MNM) has become globally recognized as an indicator of pregnancy, birth and the first 42 days of postpartum care services. The World Health Organization has taken a new approach to detail and better analyze maternal deaths. The clinic-based criteria to evaluate maternal care and the quality of related care services have been developed.
View Article and Find Full Text PDFPostpartum furosemide for accelerating recovery in patients with preeclampsia: A Randomized Placebo-Controlled Trial: Furosemide for postpartum hypertension.
Am J Obstet Gynecol MFM
January 2025
Instituto de Medicina Integral Prof. Fernando Figueira (IMIP), Recife, Pernambuco, Brazil.
Background: Preeclampsia is a major hypertensive disorder of pregnancy, which may lead to severe complications, particularly in the first two weeks of the postpartum period. During the postpartum period, blood pressure levels remain high, often increasing to levels higher than those experienced during pregnancy. Furosemide, a fast-acting diuretic, reduces the intravascular volume overload and may represent an alternative to accelerate the normalization of blood pressure levels.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!