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Introduction: Focused assessment with sonography in trauma (FAST) is historically an effective method of assessing the patient in the trauma bay in order to aid decision-making and optimise patient outcomes. However, in the UK civilian practice, the use of FAST may decline given a recent change in National Institute for Health and Care Excellence guidance as a result of improvement in CT availability and resuscitation techniques.
Method: In the Role 3 Medical Treatment Facility, Camp Bastion, 187 patients with trauma who received FAST in the trauma bay in 2014 were reviewed to determine the accuracy of FAST in the deployed environment.
Results: The data demonstrates the sensitivity and specificity of FAST to be 75% and 99.3%, respectively.
Conclusions: This study demonstrates that FAST is accurate on operations. FAST is provided by the integrated radiologist as part of damage control radiology, which gives the team leader rapid diagnostic information to improve decision-making and ultimately patient outcomes. CT is heavily utilised in civilian practice; however, the military operates in a different environment often with multiple casualties and limited access to CT, as a result, portable ultrasound will continue to be a valuable tool on operations if used properly. The next challenge is to develop and maintain this high diagnostic accuracy in future deployments where the memories of our prior success may fade.
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http://dx.doi.org/10.1136/jramc-2018-000906 | DOI Listing |
Prenat Diagn
March 2025
Division of Neonatology, Department of Pediatrics, NYU Langone Hospital-Long Island, New York University Grossman Long Island School of Medicine, Mineola, New York, USA.
Objective: Recent guidelines suggest that non-invasive prenatal screening (NIPS) should be offered to all patients with singleton and twin pregnancies. Accurate determination of fetal fraction in cell-free DNA (cfDNA) is vital for reliable NIPS outcomes. We propose a methylation-based approach using droplet digital PCR (ddPCR) and methylation-sensitive restriction enzyme (MSRE) digestion for fetal fraction quantification as an affordable and fast solution.
View Article and Find Full Text PDFTransplant Proc
March 2025
Department of Urology, Singapore General Hospital, Singapore, Singapore. Electronic address:
Background And Objective: Natural language processing (NLP) is a subfield of artificial intelligence that enables computers to process human language. As most human interactions today involve the internet and electronic devices, NLP tools quickly become indispensable to modern life. The use of NLP tools in medical practice and research is growing fast.
View Article and Find Full Text PDFUltrasonics
May 2025
Department of Building Environment and Energy Engineering, The Hong Kong Polytechnic University, Hong Kong, China; Division of Science, Engineering and Health Studies, College of Professional and Continuing Education, The Hong Kong Polytechnic University, Hong Kong, China. Electronic address:
SAW (surface acoustic wave)-based microfluidics is fast becoming a recognised method for isolating and concentrating particles given its capacity for safe and label-free particle manipulation. However, widespread adoption of acoustofluidics for clinical and industrial applications is hindered by its limited capability handling submicron particles. Smaller particles, which are primarily influenced by the acoustic streaming effect, can be captured and enriched by streaming-induced vortices.
View Article and Find Full Text PDFBMJ Open Ophthalmol
March 2025
Ophthalmology, Mass Eye and Ear, Boston, Massachusetts, USA
Background/aims: To investigate the association between plasma metabolomic profiles and treatment response after intravitreal anti-vascular endothelial growth factor (VEGF) injections in treatment-naïve neovascular age-related macular degeneration (nAMD).
Methods: This is part of a prospective longitudinal study that included patients with treatment-naïve nAMD who have undergone three loading intravitreal anti-VEGF injections. All patients underwent ophthalmological examinations including spectral domain optical coherence tomography (SD OCT).
BMJ Open
March 2025
Department of Optometry, College of Medicine and Health Sciences, Comprehensive Specialized Hospital, University of Gondar, Gondar, Ethiopia.
Objective: This study aimed to assess the prevalence of diabetic macular oedema and its associated factors among adult patients with diabetes attending comprehensive specialised hospitals in Northwest Ethiopia in 2023.
Design: An institution-based, cross-sectional study.
Setting: The study was conducted at the University of Gondar, Felege Hiwot and Debre Markos comprehensive specialised hospitals in Northwest Ethiopia from 8 May to 15 June 2023.
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