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Insulin Therapy for Acute Pancreatitis in a Patient With Lipase Maturation Factor 1 Mutation: A Case Report.
J Community Hosp Intern Med Perspect
January 2025
Department of Medicine, Division of General Internal Medicine, University of Tennessee Health Science Center, Memphis, TN, USA.
Acute pancreatitis is a frequent cause of hospital admission, managed with intravenous (IV) fluids, analgesia, and oral feeding when tolerated. In patients with hypertriglyceridemia-induced pancreatitis, insulin and other therapies may be necessary for disease resolution. We present a case of a patient with severe acute pancreatitis and euglycemic diabetic ketoacidosis (DKA) with known lipase maturation factor 1 (LMF1) gene mutations, which can impact insulin efficacy on triglyceride metabolism through altered lipoprotein lipase activity, successfully treated with intravenous insulin.
View Article and Find Full Text PDFAvoidant/Restrictive Food Intake Disorder in a Pediatric Obese Patient.
Cureus
December 2024
Pediatrics, Dr. Efrain Flores Pediatrics, Bolingbrook, USA.
Avoidant/restrictive food intake disorder (ARFID) can present with limited food variety, intake, or aversions. The symptoms can manifest at any age and typically appear in the first few years of life. The prevalence of ARFID varies widely among clinical and non-clinical populations, and its diagnosis requires trained health professionals to ensure early detection and prevention of poor outcomes.
View Article and Find Full Text PDFALKBH5 alleviates lower extremity arteriosclerosis by regulating ITGB1 demethylation and influencing macrophage polarization.
Heliyon
January 2025
The First Affiliated Hospital of Bengbu Medical University, Department of Vascular Surgery, 287 Changhuai Road, Bengbu, 233004, China.
Objective: M6A methylation-regulated macrophages play an important role in the occurrence and development of arteriosclerosis. However, their role in lower extremity arteriosclerosis remains unclear. Therefore, this study aims to explore the key factors that regulate arteriosclerosis methylation in the lower extremities and the mechanism by which they affect arteriosclerosis by influencing macrophage polarization.
View Article and Find Full Text PDFExperience of home monitoring of children with complex CHD during the COVID-19 pandemic: lessons learnt.
Cardiol Young
January 2025
Paediatric Cardiology Department, Royal Belfast Hospital for Sick Children, Belfast, Northern Ireland.
Objective: The COVID-19 pandemic presented unique challenges to global healthcare. Face-to-face outpatient care was dramatically reduced. This study implemented a remote consultation service via a mobile app (Pexip) to monitor patients with major CHD.
View Article and Find Full Text PDFCognitive behavioral therapy for adolescents with eating disorders, with particular regard to clinical perfectionism.
Psychiatr Pol
October 2024
Katedra Psychologii Klinicznej i Psychoprofilaktyki, Instytut Psychologii, Uniwersytet Szczeciński.
Eating disorders are a considerable and prevalent problem among adolescents. Due to their significant adverse health consequences, it is of key importance to examine available treatment options and their effects. Despite the shared criteria for eating disorders in adolescents and adults, the diagnostic and therapeutic processes in the former require distinct specialist interventions, including the entire family environment.
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