Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5329242 | PMC |
Publication Analysis
Top Keywords
Similar Publications
Functional screening identifies miRNAs with a novel function inhibiting Vascular Smooth Muscle Cell proliferation.
Mol Ther
December 2024
Centre for Cardiovascular Science, The Queen's Medical Research Institute, University of Edinburgh; Edinburgh EH16 4TJ, UK; CARIM school for cardiovascular sciences, Department of Pathology, Maastricht University Medical Center (MUMC); Maastricht 6229HX, The Netherlands. Electronic address:
Proliferation of vascular smooth muscle cells (vSMCs) is a crucial contributor to pathological vascular remodelling. MicroRNAs (miRNAs) are powerful gene regulators and attractive therapeutic agents. Here, we aim to systematically identify and characterise miRNAs with therapeutic potential in targeting vSMC proliferation.
View Article and Find Full Text PDFThe psychometric properties of the EQ-HWB and EQ-HWB-S in patients with breast cancer: a comparative analysis with EQ-5D-5L, FACT-8D and SWEMWBS.
Value Health
December 2024
Department of Health Policy, Corvinus University of Budapest, Hungary, Budapest.
Objectives: The EQ Health and Well Being is a new generic measure that captures constructs beyond health-related quality of life, with a 25-item long form (EQ-HWB) and a shorter 9-item version (EQ-HWB-S). This study aims to assess the psychometric performance of both versions in breast cancer, which is the most prevalent cancer globally, and compare them to other instruments.
Methods: A longitudinal survey in Indonesia (2023-24) with 300 female patients used the EQ-HWB, EQ-5D-5L, Functional Assessment of Cancer Therapy-General (FACT-G, from which FACT-8D was derived), Warwick-Edinburgh Mental Wellbeing Scale (WEMWBS, from which SWEMWBS was derived).
Oleogelation for saturated fat replacement in vegan cheese.
Food Chem
December 2024
Institute of Biological Chemistry, Biophysics and Bioengineering, School of Engineering and Physical Sciences, Heriot-Watt University, Edinburgh, UK; Dept. of Physics, Toronto Metropolitan University, Toronto, Canada. Electronic address:
Oleogelation was investigated to reduce the saturated fat content of vegan cheese. Oleogels were formulated using a range of oleogelators, oleogelator concentrations and oil phase compositions to study the effect that adjusting these parameters had on both oleogel and vegan cheese properties. Comparing oleogels at an equivalent mass basis of 20 wt%, phytosterol oleogels exhibited greater hardness (5.
View Article and Find Full Text PDFLongitudinal associations between air pollution and incident dementia as mediated by MRI-measured brain volumes in the UK Biobank.
Environ Int
December 2024
MRC Centre for Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, UK; National Institute for Health Research Health Protection Research Unit in Chemical and Radiation Threats and Hazards, School of Public Health, Imperial College London, UK. Electronic address:
Background: Although there is increasing evidence that environmental exposures are associated with the risk of neurodegenerative conditions, there is still limited mechanistic evidence evaluating potential mediators in human populations.
Methods: UK Biobank is a large long-term study of 500,000 adults enrolled from 2006 to 2010 age 40-69 years. ICD-10 classified reports of dementia cases up to 2022 (Alzheimer's disease, vascular dementia, dementia in other classified diseases, and unspecified dementia) were identified from health record linkage.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!