We need to be aware of rare causes of persistent thrombocytopenia as Bernard-Soulier syndrome (BSS). When BSS is suspected based on family history and giant platelets, genetic test for mutations of GPIbIXV is necessary. Management varies once you recognize the cause. Platelets transfusion and antifibrinolytics are the mainstay of therapy.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889233 | PMC |
| http://dx.doi.org/10.1002/ccr3.1427 | DOI Listing |
Publication Analysis
Top Keywords
bernard-soulier syndrome
8
point mutation
4
mutation phe71ser
4
phe71ser glycoprotein
4
glycoprotein genetic
4
genetic bernard-soulier
4
syndrome case
4
case report
4
report aware
4
aware rare
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!