AI Article Synopsis
- A 31-year-old Filipino man with a history of chronic methamphetamine use developed tetanus after a skin graft on his fractured heel became necrotic.
- His muscle spasms were resistant to standard treatment with benzodiazepines, which usually help manage such symptoms.
- Ultimately, his muscle spasms were effectively controlled using rocuronium and midazolam, and he was discharged after 30 days of treatment, having improved significantly.
Article Abstract
This is a case of a 31-year-old Filipino man with chronic methamphetamine use disorder who developed tetanus from a necrotic skin graft over his left calcaneus, which was fractured after a motor vehicular accident. During the course of his illness, the patient's muscle spasms were unusually refractory to benzodiazepine, which is the first-line drug used in the management of muscle spasms. The muscle spasms were successfully controlled on the seventh day of illness with rocuronium at a dose of 10 μg/kg/min and midazolam at 0.30 mg/kg/hour. Both infusions were tapered off until the 23rd day of illness. The patient was discharged on the 30th day of illness, improved and stable.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893990 | PMC |
| http://dx.doi.org/10.1136/bcr-2018-224391 | DOI Listing |
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