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cGMP-dependent protein kinase II and aldosterone secretion.
FEBS J
February 2009
Institut für Pharmakologie und Toxikologie, Medizinische Fakultät, Technische Universität München, Germany.
ACTH-stimulated aldosterone secretion can be inhibited by atrio-natriuretic peptide/cGMP. The mechanism behind this modulation has been reported to involve cGMP-dependent activation of phosphodiesterase 2 (PDE2) and hydrolysis of cAMP. Recently it was reported that activation of cGMP-dependent protein kinase II (cGKII) stimulated aldosterone secretion in rat zona glomerulosa cells.
View Article and Find Full Text PDFActivation of renal dopamine system by physical exercise.
Hypertens Res
June 1995
Department of Internal Medicine, School of Medicine, Fukuoka University, Japan.
Physical exercise is one of the life-style modifications used for lowering blood pressure. Except for diminished norepinephrine spill over, the mechanism by which physical exercise exerts its effects was not known. Based on our preliminary finding that the reduction of blood pressure was inversely correlated to the baseline plasma renin activity, we have consequently revealed that mild exercise reduces plasma volume and hence the cardiac index.
View Article and Find Full Text PDF[Atrial natriuretic factor in congenital heart defects in infants].
Cesk Pediatr
August 1993
IV. Detská klinika IVZ pri Detskej nemocnici, Kosice.
The authors examined the level of the atrio-natriuretic factor (ANF) in 7 infants with inborn heart disease at the age of 3 weeks to 5.5 months. As controls they examined 9 convalescent infants aged 1-10 months.
View Article and Find Full Text PDFDuring a 25-day space mission of French cosmonaut on board Mir station, the joint Soviet-French Czecho-Slovak experiment "Minilab" has been conducted in order to evaluate a fluid-electrolyte metabolism status and its hormonal control at different flight stages and early postflight. In cosmonaut venous blood was drawn twice, and 24-hour urine samples were collected on mission Days 5 and 19. With the aid of Plasma-02 equipment the blood plasma and urinary samples were treated, frozen and maintained aboard the station.
View Article and Find Full Text PDFThe atrio-natriuretic hormone physiologic effects.
Endocrinologie
March 1988
C. I. Parhon Institute of Endocrinology, Bucharest, Romania.
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