Vaginal Microbiomes Associated With Aerobic Vaginitis and Bacterial Vaginosis.

Front Public Health

Genital Mucosal HIV and STI Research Group, Division of Medical Virology, Department of Pathology, Faculty of Health Sciences, University of Cape Town, Medical Virology Laboratory, Cape Town, South Africa.

Published: March 2018

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Article Abstract

A healthy vaginal microbiota is considered to be significant for maintaining vaginal health and preventing infections. However, certain vaginal bacterial commensal species serve an important first line of defense of the body. Any disruption of this microbial barrier might result in a number of urogenital conditions including aerobic vaginitis (AV) and bacterial vaginosis (BV). The health of the vagina is closely associated with inhabitant microbiota. Furthermore, these microbes maintain a low vaginal pH, prevent the acquisition of pathogens, stimulate or moderate the local innate immune system, and further protect against complications during pregnancies. Therefore, this review will focus on vaginal microbial "health" in the lower reproductive tract of women and on the physiological characteristics that determine the well-being of reproductive health. In addition, we explore the distinct versus shared characteristics of BV and AV, which are commonly associated with increased risk for preterm delivery.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879096PMC
http://dx.doi.org/10.3389/fpubh.2018.00078DOI Listing

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