Background: Clostridium perfringens is an uncommon pathogen in endophthalmitis, causing rapid destruction of ocular tissues. Clostridium perfringens infection typically occurs after penetrating injury with soil-contaminated foreign bodies.
Case Report: Here, we describe the case of a 17-year-old male who sustained a penetrating injury with a metallic intraocular foreign body and who rapidly developed severe C. perfringens panophthalmitis with orbital cellulitis. He was managed by systemic and intravitreal antibiotics, resulting in preservation of the globe, but a poor visual outcome.
Conclusion: Clostridial endophthalmitis secondary to penetrating injuries is a fulminant infection, almost always resulting in loss of the globe in the case of advanced infection. When feasible, early vitrectomy and intravitreal antibiotics should be considered in patients with penetrating eye injuries with contaminated foreign bodies.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5892009 | PMC |
| http://dx.doi.org/10.1186/s12886-018-0751-0 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
alpha toxin enteritis associated with pulmonary disease in a neotropical otter (, Olfers, 1818) under human care.
Braz J Vet Med
December 2024
Veterinarian, DSc. DMCV, IV, UFRRJ. Seropédica, RJ, Brazil.
alpha toxin (CPA) is an important enterotoxemic pathogen linked to gastrointestinal disorders and previously associated with pulmonary disease in other mammals. A young female neotropical otter presented with lethargy, anorexia and steatorrhea, which developed within 24 hours. Veterinary care was provided under anesthesia, during which dehydration, intestinal hypermotility and pulmonary crackling sounds were identified.
View Article and Find Full Text PDFAgglutination of Escherichia coli, Clostridium perfringens, and Salmonella enterica through competitive exclusion using potassium chloride with gum arabic.
Int Microbiol
December 2024
Research Institute for Bioscience Products & Fine Chemicals, Ajinomoto Co., Inc., 1-1 Suzuki-Cho, Kawasaki-Ku, Kawasaki City, Kanagawa Prefecture, 210-8681, Japan.
Bacterial infections causing necrotic enteritis and diarrhea pose a considerable economic loss to the animal industry. Using mannose oligosaccharides as competitive exclusion agents is an alternative method to antibiotic growth promoters; however, these materials are rapidly metabolized by gut microbiota, posing a challenge in sustaining their efficacy. The aim of this study was to identify an agglutination material that is effective against pathogens.
View Article and Find Full Text PDFThe efficacy of egg albumin nanoparticles adjuvanted Clostridium perfringens type D toxoid vaccine in rabbits.
Braz J Microbiol
December 2024
Institute of Microbiology, Faculty of Veterinary Science, University of Agriculture, Faisalabad, 38040, Pakistan.
Epsilon toxin (ETX) is an exotoxin produced by Clostridium perfringens type D that induces enterotoxaemia or necrotic intestinal infection in small ruminants and bovine. Immunization is an essential element in preventing the spread of infectious diseases. In recent literature, nanocarriers have exhibited the capacity to deliver protection, stability, and regulated distribution properties to protein-based antigens.
View Article and Find Full Text PDFEpsilon Toxin from Induces the Generation of Extracellular Vesicles in HeLa Cells Overexpressing Myelin and Lymphocyte Protein.
Toxins (Basel)
December 2024
Department of Pathology and Experimental Therapeutics, Faculty of Medicine and Health Sciences-Campus Bellvitge, University of Barcelona, 08907 Barcelona, Spain.
Epsilon toxin (ETX) from is a pore-forming toxin (PFT) that crosses the blood-brain barrier and binds to myelin structures. In in vitro assays, ETX causes oligodendrocyte impairment, subsequently leading to demyelination. In fact, ETX has been associated with triggering multiple sclerosis.
View Article and Find Full Text PDFEffects of drinking water supplemented with essential oils and organic acids mixtures on growth performance and intestinal health of broilers challenged with necrotic enteritis.
Poult Sci
December 2024
State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing, China. Electronic address:
It is urgent to develop effective antibiotic alternatives for the control of subclinical necrotic enteritis (NE) in chickens after in-feed antibiotics have been banned. The current study investigated the efficacy of drinking water supplemented with essential oils and organic acids mixtures (EOA) on growth performance and intestinal health of broilers challenged with necrotic enteritis (NE). A total of 360 one-day-old Arbor Acres male broilers were randomly divided into 5 treatment groups, including non-challenged control group (T0), challenged NE group (T1), and challenged NE chickens treated with 0.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!