As a new nanomaterial, graphene demonstrates great potential as an electrode for biomedical applications in sensing molecules and cells. Thus, development of biosensors based on graphene is gaining much interest due to its exceptional properties such as, large surface-to-volume ratio, high conductivity and high flexibility. In this work a liquid gated graphene field effect transistor based biosensor model is analytically developed for electrical detection of Escherichia Coli O157:H7 bacteria. The effect of graphene functionalization on the graphene conductance in the presence of E. coli is investigated. E. coli absorption effects on the graphene surface in the form of conductance variation are considered. Therefore the graphene conductance as a function of E. coli concentration which controls the current–voltage characteristics of biosensors is presented. According to the simulated results, the proposed sensor model can be applied as a powerful tool to predict the biosensor performance.
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http://dx.doi.org/10.1166/jnn.2017.12537 | DOI Listing |
J Phys Chem A
January 2025
Key Lab of Advanced Transducers and Intelligent Control System, Ministry of Education and Shanxi Province, College of Physics and Optoelectronics, Taiyuan University of Technology, Taiyuan 030024, China.
Plasmon resonance plays an important role in improving the detection of biomolecules, and it is one of the focuses of research to use metal plasmon resonance to achieve fluorescence enhancement and to improve detection sensitivity. However, the problems of nondynamic tuning and fluorescence quenching of metal plasmon resonance need to be solved. Graphene surface plasmon resonance can be dynamically controlled, and the graphene adsorption of fluorescent molecules can avoid fluorescence quenching and greatly improve the fluorescence emission intensity.
View Article and Find Full Text PDFInorg Chem
January 2025
Testing and Analysis Center, Hebei Normal University, Shijiazhuang 050024, China.
The bipyridyl tantalum complex (2,6-PrCHO)Ta(bipy) () is synthesized by the reaction of (2,6-PrCHO)TaCl () and 2,2'-bipyridine in the presence of excess potassium graphite (KC). Complex coordinates readily with pyridine and 4-(dimethylamino)pyridine (dmap) to form Lewis base adducts (2,6-PrCHO)Ta(bipy)(L) (L = py (), dmap ()), and it exhibits rich redox reactivity toward small molecules: (a) single electron transfer (SET) occurs upon exposure of to phenyl sulfide or selenide dimer, giving the open-shell, bipy-centered radical complexes (2,6-PrCHO)Ta(bipy)(PhE) (E = S (), Se ()). (b) Regioselective C-C σ-bond formation via radical coupling is observed in the SET reaction of and aldehydes, ketones, or imines to furnish insertion products -, namely, sterically more crowded benzophenone, acetophenone, 2,6-dichlorobenzaldehyde, and benzophenone imine couple with C6 or C6' of bipy in , respectively, whereas sterically less hindered benzaldehyde, cyclohexanone, and benzylideneaniline couple with C2 or C2' of bipy, respectively.
View Article and Find Full Text PDFAnalyst
January 2025
Department of Engineering Design, Indian Institute of Technology Madras, India.
High throughput intracellular delivery of biological macromolecules is crucial for cell engineering, gene expression, therapeutics, diagnostics, and clinical studies; however, most existing techniques are either contact-based or have throughput limitations. Herein, we report a light-activated, contactless, high throughput photoporation method for highly efficient and viable cell transfection of more than a million cells within a minute. We fabricated reduced graphene oxide (rGO) nanoflakes that was mixed with a polydimethylsiloxane (PDMS) nanocomposite thin sheet with an area of 3 cm and a thickness of ∼600 μm.
View Article and Find Full Text PDFSmall Methods
January 2025
Fujian Provincial Key Laboratory of Functional Marine Sensing Materials, College of Material and Chemical Engineering, Minjiang University, Fuzhou, 350108, P. R. China.
The cost-effective and scalable synthesis and patterning of soft nanomaterial composites with improved electrical conductivity and mechanical stretchability remains challenging in wearable devices. This work reports a scalable, low-cost fabrication approach to directly create and pattern crumpled porous graphene/NiS nanocomposites with high mechanical stretchability and electrical conductivity through laser irradiation combined with electrodeposition and a pre-strain strategy. With modulated mechanical stretchability and electrical conductivity, the crumpled graphene/NiS nanocomposite can be readily patterned into target geometries for application in a standalone stretchable sensing platform.
View Article and Find Full Text PDFJ Phys Chem Lett
January 2025
School of Chemical Engineering and Light Industry, Guangdong University of Technology, Guangzhou 510006, People's Republic of China.
Efficient capture of single-stranded DNA (ssDNA) is crucial for high-throughput sequencing, which influences the speed and accuracy of genetic analysis. Electrophoresis (EP) and electro-osmotic flow (EOF) have a significant impact on the translocation behavior of ssDNA through the nanopore. Experimentally, dynamically tracking these two effects remains challenging, and conventional numerical methods also struggle to capture their dynamic properties in the presence of DNA.
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