AI Article Synopsis

  • The study investigates the link between how soon a smoker has their first cigarette after waking and the risk of developing obstructive respiratory issues, such as chronic obstructive pulmonary disease (COPD).
  • Researchers analyzed data from 392 current smokers, distinguishing those who smoked within 30 minutes of waking (early group) from those who waited longer (late group).
  • Findings showed that smokers who had their first cigarette within 30 minutes had over twice the risk of obstructive pulmonary impairment compared to those who waited longer, suggesting this timing could be a key factor in assessing risk for respiratory diseases.

Article Abstract

Background: Time to first cigarette after waking is an indicator of nicotine dependence. We aimed to identify the association between time to first cigarette and spirometry-proven obstructive respiratory impairment, especially chronic obstructive pulmonary disease, in current smokers.

Methods: We included 392 subjects who visited the comprehensive medical examination center of Hallym University Sacred Heart Hospital between July 2014 and September 2015. Subjects with lung disease or anemia were excluded. Obstructive pulmonary impairment was defined as <70% of the predicted value of forced expiratory volume in 1 second/forced vital capacity. Subjects were classified into the early (≤30 minutes) and late (>30 minutes) groups based on the time to first cigarette. Logistic regression and linear regression analyses were used for data analysis.

Results: Ninety-eight subjects (25%) were classified into the early group. After adjusting for smoking behaviors (cigarettes per day and smoking duration), socioeconomic status (education and income), age, and physical activity, an early time to first cigarette was found to be associated with an increased risk of obstructive pulmonary impairment measured using spirometry (adjusted odds ratio, 2.84; 95% confidence interval, 1.22-6.61).

Conclusion: Compared to current smokers with a late time to first cigarette, those with an early time to first cigarette had a higher risk of obstructive pulmonary impairment, especially chronic obstructive pulmonary disease. Classifying smoking-related behaviors, especially time to first cigarette, may help target clinical screening for chronic obstructive pulmonary disease.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5876051PMC
http://dx.doi.org/10.4082/kjfm.2018.39.2.67DOI Listing

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