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The effect of supplementary parenteral nutrition with different energy intakes on clinical outcomes of patients after gastric cancer surgery.
BMC Surg
December 2024
General Surgery Section, Zherong County Hospital, No. 8 Shangqiao Road, Ningde, Fujian, 355300, China.
Background: To investigate the effect of postoperative supplementary parenteral nutrition (SPN) containing varying energy intake levels during the early postoperative period on the clinical outcomes of patients diagnosed with gastric cancer.
Methods: Data from 237 patients, who were diagnosed with gastric cancer between January 2016 and June 2022, were retrospectively analyzed. Patients were divided into 2 groups based on mean daily SPN energy intake: low (L-SPN; < 20 kcal/kg/day); and high (H-SPN; ≥ 20 kcal/kg/day).
Acute T cell mediated rejection of allografts remains a significant risk factor for early graft loss. Our prior work defined a population of graft-specific CD8 T cells positive for the activated receptor CD43 (expressing the 1B11 epitope) that form during acute rejection, leading us to further understand the in vivo fate and clinical relevance of this population. We found that during acute rejection, the CD43 ICOS phenotype was sensitive for proliferative graft-specific CD8 T cells.
View Article and Find Full Text PDFA Prospective Study on the Suprapatellar Approach for Tibial Shaft Fractures: Insights Into Functional and Radiological Outcomes.
Cureus
November 2024
Orthopedics and Traumatology, KIMS - Saveera Hospital, Anantapur, IND.
Background: Tibial shaft fractures are among the most common long bone injuries and often can be challenging to manage surgically. While infrapatellar (IP) intramedullary nailing (IMN) has been a widely accepted treatment, its limitations have led to the emergence of alternative approaches, such as suprapatellar nailing (SPN) in a semi-extended knee position.
Aim: To evaluate the clinical, radiological, and functional outcomes of tibial shaft fractures treated with an SPN approach in a semi-extended knee position.
Mitochondrial calcium uptake declines during aging and is directly activated by oleuropein to boost energy metabolism and skeletal muscle performance.
Cell Metab
November 2024
Nestlé Institute of Health Sciences, Nestlé Research, Société des Produit Nestlé S.A., EPFL Innovation Park, 1015 Lausanne, Switzerland. Electronic address:
Article Synopsis
- Mitochondrial calcium uniporter (MCU) plays a crucial role in calcium uptake and energy metabolism, especially during muscle contractions, but its therapeutic potential in aging-related muscle decline is not well understood.
- Research reveals that the regulator MCUR1 is downregulated in aging muscles, leading to reduced mitochondrial calcium uptake and impaired energy production, contributing to sarcopenia (muscle loss).
- The natural compound oleuropein has been identified as an activator of MCU, which enhances mitochondrial function and endurance in both young and older mice, indicating its potential as a food-derived treatment for age-related muscle dysfunction.
Static pinning synchronization control of self-triggered coupling dynamical networks.
Neural Netw
February 2025
the School of Automation, Nanjing University of Science and Technology, Nanjing, PR China. Electronic address:
In this paper, a new static pinning intermittent control based on resource awareness triggering is proposed. A multi-layer control technique is used to synchronize the coupled neural network. First, a hierarchical network structure including pinned and interaction layers is induced using each pinning strategy.
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