RNA capping by mitochondrial and multi-subunit RNA polymerases.

Transcription

a Centre for Bacterial Cell Biology , Institute for Cell and Molecular Biosciences , Newcastle University, Newcastle upon Tyne , NE2 4AX , UK.

Published: December 2018

Recently, it was found that bacterial and eukaryotic transcripts are capped with cellular cofactors installed by their respective RNA polymerases (RNAPs) during transcription initiation. We now show that mitochondrial RNAP efficiently caps transcripts with ADP - containing cofactors. However, a functional role of universal RNAP - catalysed capping is not yet clear.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150613PMC
http://dx.doi.org/10.1080/21541264.2018.1456258DOI Listing

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