The risk-benefit profile of neonatal circumcision is not clear. Most studies have focused on urinary tract infections but other health sequelae have not been evaluated. While evidence supports benefits of circumcision, a lack of randomized trials has been cited as a weakness. National guidelines provide mixed recommendations regarding neonatal circumcision. We review the weight of evidence and utilize current statistical methodology on observational data to examine the risks and benefits of neonatal circumcision.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119846PMC
http://dx.doi.org/10.5534/wjmh.180006DOI Listing

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