The main objective of this study was determining the prevalence and antibiotics resistance pattern of and sp. from diarrheal patients attending Nekemte Referral Hospital. A total of 422 patients were included in the study and their sociodemographic and clinical information was collected using questionnaire. Stool samples of the patients were collected and processed following standard bacteriological protocols. Presumptive colonies of and species were identified and subcultured to their respective genera by standard biochemical tests. Antibiotics susceptibility of the isolates was tested using disk diffusion assay. The prevalences of sp. among the patients were 7.1% and 2.1%, respectively. The antimicrobial susceptibility test results of the isolates showed that they are highly resistant to amoxicillin (30 g). In contrast, the isolates showed relatively lower resistance level to ceftriaxone (30 g), nalidixic acid (30 g), norfloxacin (10 g), and ciprofloxacin (5 g). This study revealed 9.2% prevalence of and sp. which were resistant to commonly prescribed antibiotics. Thus, intervention measures such as health education, provision of safe drinking water, improvement of waste disposal systems, and surveillance of antibiotics susceptibility of the pathogens should be done regularly.
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http://dx.doi.org/10.1155/2018/9214689 | DOI Listing |
Front Microbiol
December 2024
Faculty of Health and Life Sciences, INTI International University, Nilai, Malaysia.
Introduction: Lactic acid bacteria are prized for their probiotic benefits and gut health improvements. This study assessed five LAB isolates from Neera, with RAMULAB51 (, GenBank ON171686.1) standing out for its high hydrophobicity, auto-aggregation, antimicrobial activity, and enzyme inhibition.
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December 2024
Department of Laboratory Medicine, Guangdong Provincial Hospital of Chinese Medicine, Zhuhai, China.
Background: Previous microbiological investigations have demonstrated a significant correlation between complex (CKC) infection and mastitis. Recent studies have confirmed the existence of the CKC, with () identified as the primary infectious agent. Examining the incidence of CKC in cases of severe non-lactational mastitis, alongside the clinical characteristics of infected patients, as well as evaluating the drug sensitivity testing protocols for CKC, can provide a more robust foundation for the diagnosis and treatment of CKC infections.
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December 2024
College of Life Sciences, Zaozhuang University, Zaozhuang, China.
Introduction: The conjugative transfer of antibiotic resistance genes (ARGs) mediated by plasmids occurred in different intestinal segments of mice was explored.
Methods: The location of ARG donor bacteria and ARGs was investigated by qPCR, flow cytometry, and small animal imaging. The resistant microbiota was analyzed by gene amplification sequencing.
β-Lactams are the most widely used antibiotics for the treatment of bacterial infections because of their proven track record of safety and efficacy. However, susceptibility to β-lactam antibiotics is continually eroded by resistance mechanisms. Emerging multidrug-resistant (MDR) strains possessing altered alleles (encoding PBP2) pose a global health emergency as they threaten the utility of ceftriaxone, the last remaining outpatient antibiotic.
View Article and Find Full Text PDFArch Esp Urol
December 2024
Infectious Disease Department, Qingdao Women and Children's Hospital, 266000 Qingdao, Shandong, China.
Purpose: Urinary tract infections (UTIs) in neonates pose notable challenges in diagnosis and management because of non-specific clinical manifestations and unique physiological characteristics. Understanding the clinical features and pathogen characteristics of UTIs in this population is crucial for tailored diagnostic and therapeutic strategies. This study aimed to investigate varying clinical features and pathogen characteristics of UTIs, thereby offering a holistic perspective on the multifaceted aspects of UTIs in neonates.
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