SHR being in osmotic diuresis responded to an intravenous saline load with greater sodium excretion than WKY. Volume expansion and sodium loading did not affect the erythrocyte sodium content. Both in the non-infused and in the infused sodium-loaded state SHR had a greater Na-Li-exchange rate than WKY. In the SHR the net-22Na-gain(Ery) was not influenced by the sodium loading procedure. In WKY infusion and sodium loading induced a faster erythrocyte 22Na-uptake and a lower ouabain effect on the net-22Na-gain. The sodium metabolism differences in SHR and WKY could be due to cell membrane differences or different hormonal responses to volume and sodium loading and may be important for the sodium excretion pattern in SHR and WKY.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Color, Structure, and Thermal Stability of Alginate Films with Raspberry and/or Black Currant Seed Oils.
Molecules
January 2025
Department of Analytical Chemistry and Applied Spectroscopy, Faculty of Chemistry, Nicolaus Copernicus University in Toruń, Gagarina 7, 87-100 Toruń, Poland.
In this study, biodegradable and active films based on sodium alginate incorporated with different concentrations of oils (25% and 50%) from fruit seeds were developed for potential applications in food packaging. The ultraviolet and visible (UV-VIS) spectra of raspberry seed oil (RSO) and black currant seed oil (BCSO) indicated differences in bioactive compounds, such as tocopherols, phenolic compounds, carotenoids, chlorophyll, and oxidative status (amounts of dienes, trienes, and tetraenes) of active components added to alginate films. The study encompassed the color, structure, and thermal stability analysis of sodium alginate films incorporated with RSO and BCSO and their mixtures.
View Article and Find Full Text PDFStudy on Synergistically Improving Corrosion Resistance of Microarc Oxidation Coating on Magnesium Alloy by Loading of Sodium Tungstate and Silane Treatment.
Materials (Basel)
January 2025
Qinghai Provincial Key Laboratory of Nanomaterials and Technology, School of Chemistry and Materials Science, Qinghai Minzu University, Xining 810007, China.
Sodium tungstate (NaWO) was filled into the micropores and onto the surface of a magnesium alloy microarc oxidation (MAO) coating by means of vacuum impregnation. Subsequently, the coating was sealed through silane treatment to synergistically boost its corrosion resistance. The phase composition of the coating was inspected using XRD.
View Article and Find Full Text PDFPolydopamine nanoparticles loaded with sodium ferulate for targeted therapy of myocardial infarction in endothelial cells.
Int J Pharm
January 2025
Department of Pharmacy, the Second Affiliated Hospital, Harbin Medical University (Key Laboratory of Medications Research, College of Heilongjiang Province), Harbin 150086, China; Department of Pharmaceutics, School of Pharmacy, Harbin Medical University, Harbin 150086, China. Electronic address:
Myocardial infarction (MI) is a leading cause of heart failure and death in cardiovascular diseases. Most drug trials currently fail due to inadequate local drug activity and side effects. In this study, we developed a novel polydopamine (PDA) nano delivery system that carries sodium ferulate (SF) and is modified with RGD peptides (SF/RGD-PDA NPs) for precise targeted delivery.
View Article and Find Full Text PDFCalcium Phosphate Nanoparticles Functionalized with a Cardio-Specific Peptide.
Nanomaterials (Basel)
January 2025
Institute of Science, Technology and Sustainability for Ceramics (ISSMC), National Research Council (CNR), 48018 Faenza, Italy.
Cardiovascular diseases (CVDs) remain the leading cause of mortality worldwide, highliting the urgent need for new therapeutic strategies. Peptide-based therapies have demonstrated significant potential for treating CVDs; however, their clinical application is hindered by their limited stability in physiological fluids. To overcome this challenge, an effective drug delivery system is essential to protect and efficiently transport peptides to their intended targets.
View Article and Find Full Text PDFPolydeoxynucleotide-Loaded Visible Light Photo-Crosslinked Gelatin Methacrylate Hydrogel: Approach to Accelerating Cartilage Regeneration.
Gels
January 2025
Department of Polymer Nano Science & Technology and Polymer Materials Fusion Research Center, Jeonbuk National University, 567 Baekje-daero, Deokjin-gu, Jeonju-si 54896, Jeonbuk, Republic of Korea.
Articular cartilage faces challenges in self-repair due to the lack of blood vessels and limited chondrocyte concentration. Polydeoxyribonucleotide (PDRN) shows promise for promoting chondrocyte growth and cartilage regeneration, but its delivery has been limited to injections. Continuous PDRN delivery is crucial for effective cartilage regeneration.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!