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Post-traumatic Takotsubo Cardiomyopathy in a Pediatric Patient: A Rare Case and Diagnostic Challenge.
Cureus
November 2024
Anesthesia and Critical Care, Mohammed VI University Hospital, Tangier, MAR.
Takotsubo cardiomyopathy (TTC), also known as stress-induced cardiomyopathy, is a rare condition in children that causes acute, severe, but often reversible systolic dysfunction of the left ventricle. Physical trauma is a recognized trigger, although distinguishing TTC from myocardial contusion in pediatric trauma cases can be challenging due to overlapping clinical features. We present the case of a six-year-old boy involved in a high-impact motor vehicle collision.
View Article and Find Full Text PDFPosttraumatic Stress Disorder and the Risk of Heart Failure Hospitalizations Among Individuals With Coronary Artery Disease.
Circ Cardiovasc Qual Outcomes
December 2024
Division of Cardiology, Department of Medicine (Z.A., C.L., K.M., M.W., A.J.S., A.A.Q., V.V.), Emory University School of Medicine, Atlanta, GA.
Article Synopsis
- PTSD is linked to a higher risk of heart failure hospitalizations in individuals with coronary artery disease, with those diagnosed having a 4.4 times greater risk of hospitalizations compared to those without PTSD.
- The study involved 736 participants, revealing that 9.4% had PTSD, and higher PTSD symptom scores correlated with increased heart failure events.
- While PTSD is strongly associated with heart failure, it does not appear to influence rates of cardiovascular death or nonfatal heart attacks unrelated to heart failure hospitalizations.
[Exploring the reality of seafarers' deaths and injuries and preventive measures from the cases of overwork-related disorders].
Sangyo Eiseigaku Zasshi
November 2024
Research Center for Overwork-Related Disorders, National Institute of Occupational Safety and Health, Japan.
Objectives: Till date, only few studies have detailed the reality of overwork-related disorders among seafarers. Therefore, in this study, we aimed to evaluate the prevalence of overwork-related disorders among seafarers and assess factors such as patient attributes, diseases diagnosed at the time of determination, workload factors, and other aspects, thereby suggesting relevant preventative measures.
Methods: Among all the patients identified with overwork-related disorders from April 2010 to March 2017, 2,280 cases of cerebrovascular and cardiovascular diseases and 3,517 cases of mental disorders were selected.
Downregulation of interleukin 11 regulates the transforming growth factor-β/ERK1/2 signaling pathway to inhibit articular capsule fibrosis and alleviate post-traumatic articular capsule contracture.
J Shoulder Elbow Surg
February 2025
Department of Orthopedic Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China. Electronic address:
Background: Post-traumatic capsular contracture is a common complication of joint injury and surgery. Post-traumatic capsular contracture is associated with fibrosis characterized by excessive differentiation and proliferation of myofibroblasts and abnormal secretion and accumulation of extracellular matrix. Previous studies have suggested that interleukin 11 (IL11) plays a role in myocardial fibrosis.
View Article and Find Full Text PDFChaos control in cardiac dynamics: terminating chaotic states with local minima pacing.
Front Netw Physiol
July 2024
Computational Physics for Life Science, Nuremberg Institute of Technology Georg Simon Ohm, Nuremberg, Germany.
Current treatments of cardiac arrhythmias like ventricular fibrillation involve the application of a high-energy electric shock, that induces significant electrical currents in the myocardium and therefore involves severe side effects like possible tissue damage and post-traumatic stress. Using numerical simulations on four different models of 2D excitable media, this study demonstrates that low energy pulses applied shortly after local minima in the mean value of the transmembrane potential provide high success rates. We evaluate the performance of this approach for ten initial conditions of each model, ten spatially different stimuli, and different shock amplitudes.
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