vesicle formation and growth: an integrative approach to artificial cells.

Chem Sci

Department of Chemistry and Biochemistry , University of California, San Diego , La Jolla , CA 92093 , USA . Email:

Published: December 2017

The assembly of artificial cells provides a novel strategy to reconstruct life's functions and shed light on how life emerged on Earth and possibly elsewhere. A major challenge to the development of artificial cells is the establishment of simple methodologies to mimic native membrane generation. An ambitious strategy is the bottom-up approach, which aims to systematically control the assembly of highly ordered membrane architectures with defined functionality. This perspective will cover recent advances and the current state-of-the-art of minimal lipid architectures that can faithfully reconstruct the structure and function of living cells. Specifically, we will overview work related to the formation and growth of biomimetic membranes. These studies give us a deeper understanding of the nature of living systems and bring new insights into the origin of cellular life.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858084PMC
http://dx.doi.org/10.1039/c7sc02339aDOI Listing

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