Genetic diversity and antifungal susceptibility of Candida albicans isolated from Iranian patients.

Med Mycol

Invasive Fungi Research Center, and Department of Medical Mycology and Parasitology, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.

Published: January 2019

A total of 105 independent Candida albicans strains isolated from patients in Iran were investigated. According to CLSI documents M27-A3 and M27-S4, the 24 h geometric mean MICs of caspofungin, itraconazole, and fluconazole were 0.27, 3.19, and 11.91 μg/ml, respectively. Microsatellites analysis of CEF3, CAIII, LOC4 Loci identified 93 different allelic genotypes clustered apart into six different clades. Antifungal susceptibility was not linked with the source of isolation and the corresponding genotype of C. albicans strains.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506605PMC
http://dx.doi.org/10.1093/mmy/myy016DOI Listing

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