Comparison of ocular wavefront aberrations in subluxated lenses before and after lens extraction with intraocular lens implantation.

Purpose: To compare the change in ocular higher-order wavefront aberrations (HOAs), visual acuity, and modulation transfer function (MTF) after lens extraction with intraocular lens (IOL) implantation in patients with subluxated lenses.

Setting: Iladevi Cataract & IOL Research Centre, Ahmedabad, India.

Design: Prospective case series.

Methods: Eyes with subluxated lenses having lens extraction with IOL implantation were included. Capsular bag fixation with in-the-bag IOL implantation or sutured or sutureless scleral fixation of the IOL was performed. Aberrometry was performed preoperatively and 6 months postoperatively. The following were compared: root-mean-square (RMS) value for total ocular HOAs, coma aberration, spherical aberration, MTF, and corrected distance visual acuity (CDVA).

Results: Of the 39 eyes with subluxated lenses, 26 eyes had Cionni ring fixation, 9 had sutured scleral fixation, and 4 had intrascleral fixation of the IOL. The mean preoperative and postoperative values, respectively, were as follows: RMS HOAs, 10.5 μm ± 9.5 (SD) and 4.73 ± 4.6 μm (P < .001); coma aberration, 2.46 ± 2.4 μm and 0.11 ± 0.1 μm (P = .03); and spherical aberration, 0.37 ± 0.9 μm and 0.02 ± 0.06 μm (P = .02). The MTF improved significantly in all eyes (mean 0.05 ± 0.02 preoperatively and 0.32 ± 0.16 postoperatively) (P = .005). The CDVA was statistically significant improved 6 months postoperatively.

Conclusion: Lens extraction with IOL fixation in eyes with subluxated lenses significantly reduced ocular HOAs and improved the MTF.