[Antimicrobial susceptibility and drug-resistance genes of spp. of retailed poultry in 4 provinces of China].

Zhonghua Yu Fang Yi Xue Za Zhi

Key Laboratory of Food Safety Risk Assessment of Ministry of Health, China National Center for Food Safety Risk Assessment, Beijing 100021, China.

Published: April 2018

To monitor the antimicrobial resistance and drug-resistance genes of , and recovered from retailed fresh poultry of 4 provinces of China. The susceptibility of 25 isolated spp. to 14 classes and 25 kinds of antibiotics was determined by broth microdilution method according to CLSI (Clinical and Laboratory Standards Institute). The antibiotic resistance genes were predicted with antibiotic resistance genes database (ARDB) using whole genome sequences of spp. In all 22 tested, 63.7% (14 isolates), 22.8% (5 isolates), 4.6% and 4.6% of 1 isolates exhibited the resistance to cefoxitin, ampicillin-sulbactam, nitrofurantoin and trimethoprim-sulfamethoxazole, respectively. All the 25 isolates were multi-drug resistant to more than 3 antibiotics, while 64.0% of isolates were resistant to more than 4 antibiotics. A few isolates of this study were intermediate to ceftriaxone and ciprofloxacin. Most spp. isolates contained antibiotic resistance genes and , and 5 isolates recovered from fresh chicken also contained 1, 2 and 3. The multi-drug resistant spp. isolated from retailed fresh poultry is very serious in the 4 provinces of China, and their contained many kinds of drug-resistance genes.

Download full-text PDF

Source
http://dx.doi.org/10.3760/cma.j.issn.0253-9624.2018.04.006DOI Listing

Publication Analysis

Top Keywords

drug-resistance genes
12
antibiotic resistance
12
resistance genes
12
poultry provinces
8
retailed fresh
8
fresh poultry
8
provinces china
8
isolates
8
multi-drug resistant
8
resistant antibiotics
8

Similar Publications

Clinical and molecular analysis of ESBL, carbapenemase, and colistin-resistant bacteria in UTI patients.

Cell Mol Biol (Noisy-le-grand)

January 2025

Jiangxi Key Laboratory of Oncology (2024SSY06041), Jiangxi Cancer Hospital & Institute, The Second Affiliated Hospital of Nanchang Medical College, Nanchang, Jiangxi, 330029, P.R. China.

Uropathogens, particularly bacteria, can infect any part of the urinary tract and cause bacteriuria. Our study aimed to examine the antibiotic-resistant profile, associated risk factors, and phenotypic and genotypic features of ESBL, carbapenemase, and mcr resistance genes in multidrug-resistant bacteria. Samples were inoculated on culture media, identified using standard biochemical tests, and species confirmation was performed via 16S rRNA gene amplification.

View Article and Find Full Text PDF

Background: Wild game meat has over the years gained popularity across the globe as it is considered a food source with high protein content, low fat content, and a balanced composition of fatty acids and minerals, which are requirements for a healthy diet. Despite this popularity, there is a concern over its safety as many species of wildlife are reservoirs of zoonotic diseases including those of bacterial origin, more so antibiotic-resistant bacteria.

Methods: This study aimed to describe the prevalence of antibiotic-resistant bacteria in mammalian wild game, following the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines.

View Article and Find Full Text PDF

Controlling microbial pollutants is a significant public health concern as they cause several chronic microbial infections and illnesses. In recent years, essential oils (EOs) have become intriguing alternatives for synthetic antimicrobials due to their biodegradability, natural source extraction, and strong antibacterial properties. The bactericidal properties of alginate containing lemon essential oil were examined in this investigation.

View Article and Find Full Text PDF
Article Synopsis
  • PFOS is a chemical frequently used in industries that can enter the environment and is resistant to breakdown, leading to health concerns.
  • Recent studies show a link between PFOS exposure in humans and various diseases, highlighting its impact on human health.
  • Research indicates that PFOS negatively affects endometrial cell function and morphology, potentially leading to issues with embryo implantation due to mitochondrial damage and alterations in key protein expression.
View Article and Find Full Text PDF

Knockdown of LAMA3 enhances the sensitivity of colon cancer to oxaliplatin by regulating the Hippo-YAP pathway.

Biochim Biophys Acta Mol Basis Dis

January 2025

Department of Radiation Oncology, Zhujiang Hospital, Southern Medical University, Guangzhou City, Guangdong Province 510280, China. Electronic address:

Background: Oxaliplatin is the first-line chemotherapy for patients with colon cancer (CC). However, its resistance limits its therapeutic efficacy.

Methods: Oxaliplatin resistance-associated differentially expressed genes (DEGs) in the GSE42387 and GSE227315 datasets were identified through bioinformatics methods.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!