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http://dx.doi.org/10.1001/jama.2018.2945DOI Listing

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Article Synopsis
  • Mycobacterium marinum is a slow-growing mycobacterium that can cause skin infections, often linked to aquatic environments and affecting even healthy individuals.
  • A 23-year-old aquarium worker developed chronic skin nodules, initially misdiagnosed as tuberculosis; further biopsy confirmed M. marinum infection, leading to an adjustment in his treatment plan due to liver issues and side effects.
  • The case highlights the importance of repeated biopsies for accurate diagnosis and the complexities involved in treating infections like M. marinum, as treatment regimens are not well-established and may require trial and error.
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Goals: To evaluate the efficacy and safety of standard triple therapy (STT) in Latin America.

Background: Helicobacter pylori infection affects more than 50% of the Latin Americans and leads to gastric mucosa damage. Scarce data on effective therapeutic approaches in the region underscores the need for comprehensive information.

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Background: Acquired prolonged corrected QT (QTc) interval can lead to life-threatening Torsade de Pointes (TdP) arrhythmia. Multiple risk factors including medications, comorbidities, and electrolyte imbalances contribute significantly to acquired manifestations of the QTc prolongation. Critically ill patients are particularly more vulnerable to TdP due to complex medical conditions, aging, and polypharmacy.

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Cardiac events after using clarithromycin for anti-Helicobacter pylori therapy in patients with coronary artery disease.

Medicine (Baltimore)

November 2023

Division of Gastroenterology and Hepatology, Department of Internal Medicine, Far Eastern Memorial Hospital, Banqiao District, New Taipei City, Taiwan.

Clarithromycin is an antibiotic commonly used to treat Helicobacter pylori infections. The US Food and Drug Administration (FDA) advises caution before prescribing clarithromycin to patients with cardiac diseases. This study aimed to evaluate cardiac events after anti-H pylori treatment in patients with coronary artery disease.

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Introduction And Importance: While 14-day triple therapy with clarithromycin is a common approach for eradicating infection, it is essential to note that this treatment does not come without potential side effects.

Case Presentation: We present the case of a 34-year-old male who presented to the emergency department with severe vomiting and abdominal pain. Subsequent evaluation revealed that the patient had developed drug-induced liver injury (DILI).

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