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Advanced disconnectomic analyses reveal repetition pathways in a case of mixed transcortical aphasia.
Brain Cogn
December 2024
Department of Neuroscience, University of Padova, Italy; Padova Neuroscience Center, University of Padova, Italy. Electronic address:
Mixed Transcortical Aphasia (MTA) is an infrequent aphasic syndrome, characterized by poor comprehension and production in oral language abilities and poor performance in written language abilities. However, individuals with MTA typically retain the ability to repeat. Our patient, a woman who suffered from a left hemisphere ischemic stroke involving perisylvian areas, presented with repetition preserved for words, non-words, sentences and numbers, together with marginally preserved reading abilities.
View Article and Find Full Text PDFImmediate Implant Placement in a Hypothyroid Geriatric Patient: Aesthetic Excellence, Secondary Stability, and Successful Outcome-A Case Report.
Plast Aesthet Nurs (Phila)
December 2024
Sowmya Srinivas, BDS, MDS, PhD, is an Assistant Professor at the Department of Prosthodontics, JSS Dental College and Hospital, JSS Academy of Higher Education and Research, Mysore, Karnataka, India.
Placing an implant immediately into extraction sockets provides a distinct advantage over delayed placement, eliminating the need for a 4 to 6 months waiting period for bone formation. However, when patients present with hypothyroidism, the feasibility of immediate placement of dental implants becomes uncertain. This case involved a hypothyroid woman in her late 60s with loose lower anterior teeth.
View Article and Find Full Text PDFResponse to EGFR/NTRK/MET Co-Inhibition Guided by Paired NGS in Advanced NSCLC With Acquired EGFR L858R/T790M/C797S Mutations.
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1Division of Thoracic Tumor Multimodality Treatment, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
EGFR tyrosine kinase inhibitors (TKIs) have significantly improved clinical outcomes for patients with non-small cell lung cancer (NSCLC) harboring EGFR-activating mutations. However, resistance to TKI therapy often develops due to secondary EGFR mutations or the activation of bypass signalling pathways. Next-generation sequencing (NGS) can efficiently identify actionable genetic alterations throughout treatment.
View Article and Find Full Text PDFClinical outcomes and complications of retained biliary stents during the COVID-19 pandemic: a case series.
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January 2025
Department of Surgical Gastroenterology, Tribhuvan University Teaching Hospital, Institute of Medicine, Tribhuvan University, Kathamndu 44600, Nepal.
Biliary stents are widely used following endoscopic management of choledocholithiasis. Removal is recommended within 3-6 months to prevent complications. This study analyzed cases of retained biliary stents managed at our institution.
View Article and Find Full Text PDFThe impact of active substance on the adhesiveness of medicated patches containing liquid additives.
Eur J Pharm Sci
December 2024
Department of Pharmaceutical Technology, Faculty of Pharmacy, Medical University of Gdansk, Poland.
Adhesiveness of dermal patches can be modified in the presence of active substances. The effect is more complex when liquid components are also present in the matrix. Commercial grade pressure sensitive adhesive (PSA) polyacrylates (three types) and silicones (two types) were used to prepare adhesive matrices and liquid additives were propylene glycol, polyoxyethylene glycol, isopropyl myristate, triacetin, triethyl citrate or low viscosity silicone oil.
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