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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895868 | PMC |
| http://dx.doi.org/10.3343/alm.2018.38.4.371 | DOI Listing |
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NIR-II photo-accelerated polymer nanoparticles boost tumor immunotherapy via PD-L1 silencing and immunogenic cell death.
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Immune checkpoint blockade (ICB) therapy is a widely favored anti-tumor treatment, but it shows limited response to non-immunogenic "cold" tumors and suffers from drug resistance. Photodynamic therapy (PDT), as a powerful localized treatment approach, can convert a "cold tumor" into a "hot tumor" by inducing immunogenic cell death (ICD) in tumor cells, thereby enhancing tumor immunogenicity and promoting tumor immunotherapy. However, the effectiveness of PDT is largely hindered by the limited penetration depth into tumor tissues.
View Article and Find Full Text PDFEnhanced UV-B photoprotection activity of carotenoids from the novel sp. strain LAPM80 isolated from King George Island, Antarctica.
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Biological and Environmental Science and Engineering Division, King Abdullah University of Science and Technology, Makkah, 23955, Saudi Arabia.
Antarctica's harsh environmental conditions, characterized by high levels of ultraviolet (UV) radiation, pose challenges for microorganisms. To survive in these extreme cold regions with heightened UV exposure, microorganisms employ various adaptive strategies, including photoprotective carotenoid synthesis. Carotenoids are garnering attention in the skin health industry because of their UV photoprotection potential, given the direct relationship between UV exposure and skin burns, and cancer.
View Article and Find Full Text PDFBlue light irradiation combined with low-temperature storage further enhances postharvest quality of strawberries through improving antioxidant defense and cell wall metabolic activities.
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View Article and Find Full Text PDFReinnervation of Free Nipple Grafts Associated With Improved Erection Function.
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Equivalent reduction of Escherichia coli by rinsing hands with cold and warm water.
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Institute for Hygiene and Applied Immunology, Medical University of Vienna, Austria.
Objective: Hand washing is considered an important public health intervention to reduce the burden of communicable diseases such as gastrointestinal and respiratory tract infections. Washbasins in public restrooms are often only equipped with cold water and it can be observed that people only rinse their hands briefly after using the toilet instead of washing them properly with soap. As there are no recommendations on the optimal water temperature for efficacy, we measured the efficacy of simple hand rinsing with cold (4°C) and warm (40°C) water for 10 and 20 seconds compared to the European Norm EN 1499 reference hand wash.
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