AI Article Synopsis
- The article investigates the effects of amniotic membrane versus collagen membrane on bone healing in tibial defects in dogs.
- The study involved creating bony holes in the tibia of dogs and comparing the new bone formation in various treatment groups after 6 and 12 weeks.
- Results indicate that the amniotic membrane group showed significantly better bone formation compared to the control group, suggesting its potential benefits for guided bone regeneration.*
Article Abstract
The purpose of this article was to evaluate the bone induction effects of an amnion membrane-protected graft compared with a collagen membrane-protected graft in the repair of tibial bony defects in dogs. This study was performed using the tibial bone of dogs. After the removal of periosteum, similar holes were made with a 16-mm trephine drill (38 holes in total). For the study group, 10 holes were covered by absorbable collagen and 16 holes by amniotic membrane. In the control group, 12 holes were made and covered by the overlying soft tissue. Tibial bones were exposed after 6 and 12 weeks, and the samples were harvested and histologically processed. New bone formation was evaluated by histomorphometric study. Four Iranian mixed dogs older than 1.5 years were included in this study. The new bone formation was less in the control group when compared with the collagen group ( P = .863). The collagen group showed less bone formation than the amnion group ( P = .194), but this difference was not significant. However, bone formation in the amnion group was significantly more than in the control group ( P = .050). Using the amniotic membrane appears to accelerate bone formation in guided bone regeneration. However, further studies should investigate its clinical impact on bone healing.
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| http://dx.doi.org/10.1563/aaid-joi-D-16-00120 | DOI Listing |
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