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<PubmedArticle><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">29607984</PMID><DateCompleted><Year>2019</Year><Month>10</Month><Day>17</Day></DateCompleted><DateRevised><Year>2024</Year><Month>12</Month><Day>10</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1347-4820</ISSN><JournalIssue CitedMedium="Internet"><Volume>82</Volume><Issue>7</Issue><PubDate><Year>2018</Year><Month>Jun</Month><Day>25</Day></PubDate></JournalIssue><Title>Circulation journal : official journal of the Japanese Circulation Society</Title><ISOAbbreviation>Circ J</ISOAbbreviation></Journal><ArticleTitle>Assessment of Second- and Third-Generation Drug-Eluting Stents on Chronic Coronary Angioscopy&#x3000;- Multicenter Study on Intra-Coronary AngioScopy After Stent (MICASA) Prospective Data Analysis.</ArticleTitle><Pagination><StartPage>1830</StartPage><EndPage>1835</EndPage><MedlinePgn>1830-1835</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1253/circj.CJ-17-1396</ELocationID><Abstract><AbstractText Label="BACKGROUND">The vascular response, in terms of quality and quantity, of the second- and third-generation drug-eluting stents (2G- and 3G-DES, respectively) was assessed prospectively on coronary angioscopy (CAS).</AbstractText><AbstractText Label="METHODS&#x2004;AND&#x2004;RESULTS">The Multicenter study on Intra-Coronary AngioScopy After Stent (MICASA) is a multicenter CAS registry. A total of 107 DES (71 2G- and 36 3G-DES) were prospectively observed on CAS 8.7&#xb1;2.7 months after percutaneous coronary intervention. Neointimal coverage (NC) grade was evaluated using a 4-point grading scale, from 0 (no coverage) to 3 (complete coverage). Plaque yellow color (YC) was also assessed using a 4-point grading system, from 0 (white) to 3 (bright yellow). Max-NC (2G-DES vs. 3G-DES: 2.14&#xb1;0.68 vs. 2.44&#xb1;0.73, P=0.023); min-NC (1.07&#xb1;0.48 vs. 1.39&#xb1;0.60, P=0.002), and dominant-NC (1.57&#xb1;0.69 vs. 2.08&#xb1;0.84, P=0.002) were significantly higher and the YC grade (1.23&#xb1;0.82 vs. 0.86&#xb1;0.76, P=0.031) significantly lower in the 3G-DES group than in the 2G-DES group. There was no significant difference in the presence of thrombus (28.2% vs. 22.2%, P=0.51) between the 2G- and 3G-DES groups.</AbstractText><AbstractText Label="CONCLUSIONS">The higher NC grade and lower YC grade in 3G-DES than in 2G-DES might be associated with better long-term clinical outcome, which remains to be determined in future studies.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Miyoshi</LastName><ForeName>Toru</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Department of Cardiology, Ehime Prefectural Imabari Hospital.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Matsuoka</LastName><ForeName>Hiroshi</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Department of Cardiology, Ehime Prefectural Imabari Hospital.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kawakami</LastName><ForeName>Hideo</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Department of Cardiology, Ehime Prefectural Imabari Hospital.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dai</LastName><ForeName>Kazuoki</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Department of Cardiology, Hiroshima City Hospital.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sato</LastName><ForeName>Tetsuya</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Department of Cardiology, Okayama Red Cross Hospital.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Watanabe</LastName><ForeName>Kouki</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Department of Cardiology, Saiseikai Matsuyama Hospital.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ishihara</LastName><ForeName>Masaharu</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Division of Coronary Heart Disease, Department of Internal Medicine, Hyogo College of Medicine.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D016448">Multicenter Study</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2018</Year><Month>03</Month><Day>30</Day></ArticleDate></Article><MedlineJournalInfo><Country>Japan</Country><MedlineTA>Circ J</MedlineTA><NlmUniqueID>101137683</NlmUniqueID><ISSNLinking>1346-9843</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D003116" MajorTopicYN="N">Color</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D017023" MajorTopicYN="N">Coronary Angiography</DescriptorName><QualifierName UI="Q000379" MajorTopicYN="Y">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D003324" MajorTopicYN="N">Coronary Artery Disease</DescriptorName><QualifierName UI="Q000000981" MajorTopicYN="Y">diagnostic imaging</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D054855" MajorTopicYN="N">Drug-Eluting Stents</DescriptorName><QualifierName UI="Q000592" MajorTopicYN="Y">standards</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D058426" MajorTopicYN="N">Neointima</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D062645" MajorTopicYN="Y">Percutaneous Coronary Intervention</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011446" MajorTopicYN="N">Prospective Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D016896" MajorTopicYN="N">Treatment Outcome</DescriptorName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Coronary angioscopy</Keyword><Keyword MajorTopicYN="N">Second-generation drug-eluting stent</Keyword><Keyword MajorTopicYN="N">Third-generation drug-eluting stent</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2018</Year><Month>4</Month><Day>3</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2019</Year><Month>10</Month><Day>18</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2018</Year><Month>4</Month><Day>3</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">29607984</ArticleId><ArticleId IdType="doi">10.1253/circj.CJ-17-1396</ArticleId></ArticleIdList></PubmedData></PubmedArticle></PubmedArticleSet>