Introduction: Performance-based financing (PBF) has acquired increased prominence as a means of reforming health system purchasing structures in low-income and middle-income countries. A number of impact evaluations have noted that PBF often produces mixed and heterogeneous effects. Still, little systematic effort has been channelled towards understanding what causes such heterogeneity, including looking more closely at implementation processes.
Methods: Our qualitative study aimed at closing this gap in knowledge by attempting to unpack the mixed and heterogeneous effects detected by the PBF impact evaluation in Cameroon to inform further implementation as the country scales up the PBF approach. We collected data at all levels of the health system (national, district, facility) and at the community level, using a mixture of in-depth interviews and focus group discussions. We combined deductive and inductive analytical techniques and applied analyst triangulation.
Results: Our findings indicate that heterogeneity in effects across facilities could be explained by pre-existing infrastructural weaknesses coupled with rigid administrative processes and implementation challenges, while heterogeneity across indicators could be explained by providers' practices, privileging services where demand-side barriers were less substantive.
Conclusion: In light of the country's commitment to scaling up PBF, it follows that substantial efforts (particularly entrusting facilities with more financial autonomy) should be made to overcome infrastructural and demand-side barriers and to smooth implementation processes, thus, enabling healthcare providers to use PBF resources and management models to a fuller potential.
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http://dx.doi.org/10.1136/bmjgh-2017-000693 | DOI Listing |
JMIR Infodemiology
December 2024
Department of Computer Science, University of Saskatchewan, Saskatoon, SK, Canada.
Background: Understanding advocacy strategies is essential to improving dementia awareness, reducing stigma, supporting cognitive health promotion, and influencing policy to support people living with dementia. However, there is a dearth of evidence-based research on advocacy strategies used to support dementia awareness.
Objective: This study aimed to use posts from X (formerly known as Twitter) to understand dementia advocacy strategies during World Alzheimer's Awareness Month in September 2022.
Clin Transl Gastroenterol
December 2024
Department of Pharmacology, Penn State College of Medicine, Hershey, Pennsylvania, USA.
Introduction: Hypoalgesic inflammatory bowel disease (IBD) may provide critical insights into human abdominal pain. This condition was previously associated with homozygosity for a polymorphism (rs6795970, A1073V; 1073 val/val ) related to Na v 1.8, a voltage-gated sodium channel preferentially expressed on nociceptors.
View Article and Find Full Text PDFBiomacromolecules
December 2024
Department of Biomedical Engineering, Duke University, Durham, North Carolina 27708, United States.
The efficacy of tumor-targeted therapeutics, engineered to engage specific cellular receptors to promote accumulation and penetration, is strongly influenced by the carrier's affinity for its target and the valency of binding molecules incorporated into the carrier. Previous research has primarily focused on improving targeting by augmenting the number of binding proteins on the carrier, inadvertently raising avidity without isolating the individual effects of binding strength and valency. Herein, we precisely evaluate the impact of multivalency on tumor targeting with a recombinant approach to independently control valency, avidity, and size.
View Article and Find Full Text PDFOral Radiol
December 2024
Department of Oral, Dental and Maxillofacial Radiology, Faculty of Dentistry, Ataturk University, Erzurum, 25240, Turkey.
Objective: The aim of this study is to determine the contact relationship and position of impacted mandibular third molar teeth (IMM) with the mandibular canal (MC) in panoramic radiography (PR) images using deep learning (DL) models trained with the help of cone beam computed tomography (CBCT) and DL to compare the performances of the architectures.
Methods: In this study, a total of 546 IMMs from 290 patients with CBCT and PR images were included. The performances of SqueezeNet, GoogLeNet, and Inception-v3 architectures in solving four problems on two different regions of interest (RoI) were evaluated.
J Ultrasound
December 2024
Department of Ultrasound in Obstetrics, Gynecology, and Fetal Medicine, Yerevan State Medical University after Mkhitar Heratsi, 2 Koryun St, 0025, Yerevan, Armenia.
Objectives: Despite advancements in modern medicine, the effectiveness of in vitro fertilization (IVF) remains low. This study aimed to assess the impact of specific features of T-shaped uterine cavity malformation and its intermediate forms on reproductive function and the effectiveness of assisted reproductive technology (ART), particularly on IVF results and pregnancy outcomes.
Methods: A prospective cohort study included 388 somatically healthy patients undergoing 3D ultrasound (US) examination of the uterine cavity before embryonic transfer for IVF treatment.
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