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Actinic cheilitis: proposition and reproducibility of a clinical criterion. | LitMetric

Objectives/aims: The actinic cheilitis (AC) is a precancerous lip lesion seen as a consequence of chronic sun exposure. Clinically, the border between the lip's skin and the semimucosa could be blurred; in the more aggressive cases, leucoplakia and ulcers also represent its clinical feature. It seems that no clinical criterion is universally accepted for this disease yet. Therefore, this study was carried out to make a proposition of a clinical score to actinic cheilitis (Grade I starting from dryness of vermilion to endured ulcers representing Grade IV) and to assess its reproducibility.

Materials And Methods: Fifty subjects were assessed, most of whom were male, Caucasian farmers, with an average age of 46.12 (18-74) years. The obtained data were analysed by means of descriptive statistics and by Kappa test to assess the inter-examiners and the clinical Golden-Pattern concordance (95% CI).

Results: During calibration, 15 patients were examined three times a week by each examiner (4) until Kappa test observed =0.8 or more. In the main experiment, the inter-examiner concordance was classified between good (=0.779; <0.05) and very good (=0.925; <0.05) from the 35 examined subjects. With the Golden-Pattern, it was considered very good (=0.812; <0.05 to =0.925; <0.05).

Discussion: Four examiners with different experiences could strongly suggest that after adequate calibration, it could be well applied by examiners with as much experience as a dental student.

Conclusions: The authors concluded that the proposed classification was easily applied and had a very good reproducibility.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842833PMC
http://dx.doi.org/10.1038/bdjopen.2017.16DOI Listing

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