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Modified Center-Edge Angle in Children with Developmental Dysplasia of the Hip.
J Imaging
December 2024
Department Pediatric Orthopaedics and Traumatology, Children's University Hospital, Lenggstrasse 30, 8008 Zürich, Switzerland.
Developmental dysplasia of the hip (DDH) is a prevalent developmental condition that necessitates early detection and treatment. Follow-up, as well as therapeutic decision-making in children younger than four years, is challenging because the center-edge (CE) angle of Wiberg is not reliable in this age group. The authors propose a modification of the CE angle (MCE) to achieve comparable reliability with the CE among children younger than four and set diagnostic thresholds for the diagnosis of DDH.
View Article and Find Full Text PDFLocation-specific net water uptake and malignant cerebral edema in acute anterior circulation occlusion ischemic stroke.
AJNR Am J Neuroradiol
January 2025
From the Department of Medical Imaging (X.Q.C.,C.S.Z.,Q.H.L.,H.M.P.,J.J.T.,B.Y.L.,G.M.L.),and neurology(W.S.Z.,A.Y.L.) Nanjing Jinling Hospital, Nanjing University School of Medicine, Nanjing,Jiangsu,China; Department of radiology (B.T., X.T.,Y.X.H.,L.G.C.,C.W.S.), Changhai Hospital of Shanghai, The first affiliated hospital of Navy Medical University, Shanghai, China; Department of Medical Imaging (L.J.H.), Nanjing Jinling Hospital, the First School of Clinical Medicine, Southern Medical University, Nanjing, Jiangsu, China; Department of Medical Imaging (X.S.), Nanjing Jinling Hospital, Nanjing Medical University, Nanjing, Jiangsu, China;Department of radiology (Q.C.,X.D.Y.,), Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu, China.
Background And Purpose: Early identification of malignant cerebral edema (MCE) in patients with acute ischemic stroke is crucial for timely interventions. We aimed to identify regions critically associated with MCE using the Alberta Stroke Program Early Computed Tomography Score (ASPECTS) to evaluate the association between location-specific-net water uptake (NWU) and MCE.
Materials And Methods: This multicentre, retrospective cohort study included patients with acute ischemic stroke following large anterior circulation occlusion.
Trastuzumab deruxtecan in human epidermal growth factor receptor 2-positive breast cancer brain metastases: A systematic review and updated meta-analysis.
Cancer Treat Rev
January 2025
Division of Hematology and Oncology, University of Virginia Comprehensive Cancer Center, Charlottesville, VA, United States. Electronic address:
Background: Trastuzumab deruxtecan (T-DXd) has shown promising activity in patients with human epidermal growth factor receptor 2 (HER2)-positive breast cancer (BC) and central nervous system (CNS) involvement. In this updated meta-analysis, we explore the effectiveness of T-DXd in a large subset of patients with HER2-positive BC and CNS disease.
Methods: A systematic search was made on September 16th, 2024, for studies investigating T-DXd in the scenario of HER2-positive BC and brain metastases (BMs) and/or leptomeningeal disease (LMD).
Malignant Cerebral Edema After Cranioplasty: A Case Report and Literature Insights.
Am J Case Rep
January 2025
Department of Neurosurgery, Denver Health Hospital Authority, Denver, CO, USA.
BACKGROUND Decompressive craniectomy is a common life-saving intervention in the setting of elevated intracranial pressure. Cranioplasty restores the calvarium and intracranial physiology once swelling recedes. Cranioplasty is often thought of as a low-risk intervention.
View Article and Find Full Text PDFMosla Chinensis Extract Enhances Growth Performance, Antioxidant Capacity, and Intestinal Health in Broilers by Modulating Gut Microbiota.
Microorganisms
December 2024
Hunan Key Laboratory of Traditional Chinese Veterinary Medicine, Hunan Agricultural University, Changsha 410128, China.
This study aimed to evaluate the effects of Mosla chinensis extract (MCE) on broiler intestinal health. A total of 240 1-day-old Arbor Acres (AA) broilers (balanced for sex) were randomly allocated into four treatment groups, each with six replicates of 10 chickens. The study comprised a starter phase (days 1-21) and a grower phase (days 22-42).
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