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Fully-automated segmentation of muscle and inter-/intra-muscular fat from magnetic resonance images of calves and thighs: an open-source workflow in Python.
Skelet Muscle
December 2024
Rehabilitation Sciences Institute, University of Toronto, Toronto, ON, Canada.
Background: INTER- and INTRAmuscular fat (IMF) is elevated in high metabolic states and can promote inflammation. While magnetic resonance imaging (MRI) excels in depicting IMF, the lack of reproducible tools prevents the ability to measure change and track intervention success.
Methods: We detail an open-source fully-automated iterative threshold-seeking algorithm (ITSA) for segmenting IMF from T1-weighted MRI of the calf and thigh within three cohorts (CaMos Hamilton (N = 54), AMBERS (N = 280), OAI (N = 105)) selecting adults 45-85 years of age.
Initial experiences with dynamic, quality indicator-based multimodal tissue analysis (M-Ref) with parallel assessment of viscosity and shear wave elastography in liver parenchyma alterations1.
Clin Hemorheol Microcirc
December 2024
Institute of Biotechnology, Molecular Cell Biology, Brandenburg University of Technology Cott-bus-Senftenberg, Senftenberg, Germany.
Background And Objective: Modern ultrasound technology enables detailed tissue morphology analysis. A novel approach involves measuring viscoelasticity or viscosity. This pilot study investigates the potential of a novel high-end ultrasound system with dynamic quality indicators and the M-Ref tool.
View Article and Find Full Text PDFLong-term changes in carotid intima-media thickness according to baseline blood pressure level: J-STARS Echo study.
J Neurol Sci
December 2024
Department of Clinical Neuroscience and Therapeutics, Hiroshima University Graduate School of Biomedical and Health Sciences, Hiroshima, Japan; Department of Neurology, Iseikai Hospital, Osaka, Japan.
Background And Aims: We aimed to investigate long-term changes in carotid intima-media thickness (IMT) based on baseline blood pressure (BP) levels in non-cardioembolic stroke patients.
Methods: Patients aged 45-80 years with dyslipidemia who were not on statins before enrollment and had experienced a non-cardioembolic stroke were assigned to either the pravastatin group or the control group in a randomized trial. Patients were classified into three groups according to BP levels: normal BP (N-group: systolic BP [sBP] <140 mmHg and diastolic BP [dBP] <90 mmHg), highly elevated BP (G2 group: sBP ≥160 mmHg or dBP ≥100 mmHg), and mildly elevated BP (G1 group: the remaining patients).
Foreign bodies in the ear and nose of the Australian paediatric population: A standardised approach.
Aust J Gen Pract
November 2024
MBBS, FRACS, ENT Consultant, Surgical Treatment and Rehabilitation Service (STARS), Brisbane, Qld.
Background: Foreign bodies (FBs) in the ears and nose are common presentations among paediatric patients, necessitating prompt and appropriate management to avoid potential complications.
Objective: This article presents a standardised approach for FB retrieval based on local clinical data from a tertiary paediatric centre, addressing the challenges of identifying patients requiring specialist referral.
Discussion: The approach involves a detailed initial consultation and succinct examination to determine the most suitable retrieval method.
Diagnostic accuracy of imaging modalities for detection of spinal metastases: a systematic review and meta-analysis.
Clin Transl Oncol
October 2024
Department of Radiology and Nuclear Medicine, University Medical Center Utrecht & Utrecht University, Utrecht, The Netherlands.
Purpose: Detecting spinal metastases is highly relevant in patients with oncological disorders as it can affect the staging and treatment of their disease. We aimed to evaluate the diagnostic performance of computed tomography (CT), magnetic resonance imaging (MRI), FDG positron emission tomography (PET)/CT, bone scintigraphy (BS), and single-photon emission computed tomography (SPECT) for spinal metastases detection.
Methods: Medline, EMBASE, and Web of Science were systematically searched until March 2024 for diagnostic accuracy studies on spinal metastases detection (PROSPERO-registration: CRD42024540139).
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