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[Post-traumatic pulmonary aspergilloma]. | LitMetric

[Post-traumatic pulmonary aspergilloma].

Rev Mal Respir

CS10217, clinique universitaire de pédiatrie, CHU de Grenoble-Alpes, hôpital Couple-Enfants, 38043 Grenoble cedex 9, France; Inserm 1209, institut pour l'avancée des biosciences, 38042 Grenoble cedex 9, France. Electronic address:

Published: March 2018

Introduction: Aspergillomas occur due to colonization of a pre-existing pulmonary, bronchial or pleural cavity by Aspergillus spp. Often asymptomatic, this pathology can reveal itself by recurrent haemoptysis or when bacterial superinfections occur. Aspergillomas occurring in post-traumatic cavities are rare and their management is poorly codified.

Case Report: A child suffered from a chest wound at the age of 13 years. Two years later, investigation of recurrent haemoptysis revealed a residual pneumatocele in the right lower lobe colonized by Aspergillus spp. Initial treatment with systemic azole antifungals was unsuccessful because of digestive and ophthalmological intolerance. Surgical treatment by right lower lobectomy was finally decided on by the multidisciplinary team. This revealed an intrabronchial foreign body of vegetal type with cellulosic reinforcement, causing a polymorphic granulomatous reaction around, and associated with a proliferation of filamentous fungi including Aspergillus fumigatus. Surgery was followed by liposomal amphotericin B treatment for three weeks with a favourable outcome.

Conclusions: This clinical case illustrates the benefits of surgical management of post-traumatic aspergillomas, even in children, in order to eradicate the aspergillus implant and to remove any foreign body to prevent recurrence.

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Source
http://dx.doi.org/10.1016/j.rmr.2017.05.005DOI Listing

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