Periodontitis affects nearly half of the adult population in the United States and leads to periodontium destruction, tooth loss, and tooth mobility. Novel bioengineering has become an area of interest in dentistry, as various approaches aim to regenerate attachment apparatus around diseased teeth with the use of barriers, scaffolds, bone grafts, or biologics. This article emphasizes recent findings in the fields of stem cell/gene therapy, 3-dimensional printing, and innovative scaffold designs for future applications in clinical care.
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Clin Implant Dent Relat Res
February 2025
Department of Oral Surgery and Implantology, Goethe University, Frankfurt am Main, Germany.
Objectives: This preclinical ex vivo porcine study aimed to evaluate the effects of two flap advancement techniques and periosteal suturing (PS) on graft material displacement during primary wound closure in guided bone regeneration (GBR). Secondary objectives included assessing flap advancement and the impact of soft tissue characteristics on graft displacement.
Materials And Methods: Standardized two-walled horizontal bone defects were created in second premolar sites of pig hemimandibles.
Clin Oral Investig
January 2025
Division of Prosthodontics and Implant Prosthodontics, Department of Surgical Sciences, University of Genova, Genova, Italy.
Objectives: The present systematic review aimed to evaluate if cortical bone perforation is effective in enhancing periodontal surgery and guided bone regeneration (GBR) in humans.
Materials And Methods: Electronic search was performed in PubMed, Scopus and Cochrane CENTRAL up to October 31st, 2023. Grey literature was also searched.
Clin Adv Periodontics
January 2025
Department of Dentistry and Oral Surgery, Keio University School of Medicine, Tokyo, Japan.
Background: Successful periodontal regeneration depends on primary wound closure and interdental papilla preservation. In this case study, we introduce a novel triangle papilla access approach (T-PAA) performed under a surgical microscope for treating interdental bone defects. In this novel approach, buccal incisions were used to access root surfaces and bone defects, avoiding interdental papilla incisions and preventing papillary collapse and necrosis.
View Article and Find Full Text PDFClin Adv Periodontics
January 2025
Department of Orofacial Sciences, School of Dentistry, University of California San Francisco, San Francisco, California, USA.
Background: Gingival recession has a multifactorial etiology, involving various predisposing and precipitating factors. Non-carious cervical lesions (NCCLs) are often associated with gingival recession and pose challenges due to their complex pathodynamics. There is limited evidence regarding tunnel-based procedures combined with connective tissue grafts (CTGs) for treating recession-associated NCCLs.
View Article and Find Full Text PDFRadiol Case Rep
March 2025
Department of Radiology, Imo State University, Imo State, Nigeria.
A unique case report on campylobacter rectus infection leading to acute motor axonal neuropathy in a pediatric patient. Campylobacter rectus is an anaerobic bacterium found in the oral cavity. While it has been linked to periodontal disease, its association with acute motor axonal neuropathy (AMAN), a variant of Guillain-Barre Syndrome, remains unverified.
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