Human Enzymes for Organic Synthesis.

Angew Chem Int Ed Engl

Institute for Molecular Biotechnology, Graz University of Technology, Petersgasse 14, 8010, Graz, Austria.

Published: October 2018

Human enzymes have been widely studied in various disciplines. The number of reactions taking place in the human body is vast, and so is the number of potential catalysts for synthesis. Herein, we focus on the application of human enzymes that catalyze chemical reactions in course of the metabolism of drugs and xenobiotics. Some of these reactions have been explored on the preparative scale. The major field of application of human enzymes is currently drug development, where they are applied for the synthesis of drug metabolites.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334177PMC
http://dx.doi.org/10.1002/anie.201800678DOI Listing

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