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Mechanisms of RCD-1 pore formation and membrane bending.
Nat Commun
January 2025
Beijing National Laboratory for Condensed Matter Physics, Institute of Physics, Chinese Academy of Sciences, 100190, Beijing, PR China.
Regulator of cell death-1 (RCD-1) governs the heteroallelic expression of RCD-1-1 and RCD-1-2, a pair of fungal gasdermin (GSDM)-like proteins, which prevent cytoplasmic mixing during allorecognition and safeguard against mycoparasitism, genome exploitation, and deleterious cytoplasmic elements (e.g., senescence plasmids) by effecting a form of cytolytic cell death.
View Article and Find Full Text PDFElucidating the physicochemical interactions between fibrinogen and surfactant mixtures: Implications for pharmaceutical sciences.
Int J Biol Macromol
January 2025
Soft Matter and Molecular Biophysics Group, Department of Applied Physics and Institute of Materials (iMATUS), University of Santiago de Compostela, 15782 Santiago de Compostela, Spain.
This study investigates the physicochemical interactions between fibrinogen (Fib), a key glycoprotein in blood clotting, and a mixture of two biologically active compounds: dicloxacillin (Diclox), an antibiotic; and cetyltrimethylammonium bromide (CTAB), a cationic surfactant. Understanding these interactions is crucial for enhancing drug delivery systems and optimizing pharmaceutical formulations. Molecular docking simulations and various spectroscopic techniques, including UV-Vis, fluorescence, and circular dichroism, were employed to explore how this mixture affects the structural and functional properties of fibrinogen.
View Article and Find Full Text PDFResolving spatiotemporal dynamics in bacterial multicellular populations: approaches and challenges.
Microbiol Mol Biol Rev
January 2025
General Microbiology, Technische Universität Dresden, Dresden, Germany.
SUMMARYThe development of multicellularity represents a key evolutionary transition that is crucial for the emergence of complex life forms. Although multicellularity has traditionally been studied in eukaryotes, it originates in prokaryotes. Coordinated aggregation of individual cells within the confines of a colony results in emerging, higher-level functions that benefit the population as a whole.
View Article and Find Full Text PDFPoly(lactic acid)-based materials with enhanced gas permeability for modified atmosphere packaging of Chinese bayberry.
Int J Biol Macromol
January 2025
College of Food Science and Engineering, Inner Mongolia Agricultural University, 306 Zhaowuda Road, Hohhot, Inner Mongolia 010010, China. Electronic address:
Biodegradable plastics are increasingly utilized in packaging, driven by green chemistry and environmental responsibility. Among them, poly(L-lactic acid) (PLLA) stands out due to its biodegradability and biocompatibility. However, its limited gas permeability and selectivity hinder its application in produce preservation.
View Article and Find Full Text PDFOne-step antifouling coating of polystyrene using engineered polypeptides.
J Colloid Interface Sci
January 2025
Physical Chemistry and Soft Matter, Wageningen University & Research, Stippeneng 4 6708 WE Wageningen, The Netherlands. Electronic address:
Unwanted nonspecific adsorption caused by biomolecules influences the lifetime of biomedical devices and the sensing performance of biosensors. Previously, we have designed B-M-E triblock proteins that rapidly assemble on inorganic surfaces (gold and silica) and render those surfaces antifouling. The B-M-E triblock proteins have a surface-binding domain B, a multimerization domain M and an antifouling domain E.
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