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Less cytotoxic phthalocyanine derivative promotes in vitro wound healing compared to chlorhexidine.
J Appl Biomater Funct Mater
January 2025
Department of Prosthodontics and Periodontics, Bauru School of Dentistry, University of São Paulo, Bauru, Brazil.
The use of adjunct chemical substances in the early postoperative period of periodontal surgical procedures is recommended due to the potential risk of trauma in the operated area. Chlorhexidine digluconate mouthwash is widely used but can cause adverse effects. Phthalocyanine derivatives are being studied as an alternative, demonstrating good antimicrobial activity, especially in the self-activated form, which does not require additional light or chemicals.
View Article and Find Full Text PDFComparative study of polymeric nanoparticles and traditional agents in dental implant decontamination.
J Appl Biomater Funct Mater
January 2025
Faculty of Dentistry, Department of Periodontics, Complutense University of Madrid, Madrid, Spain.
Peri-implant diseases, such as peri-implantitis, affect up to 47% of dental implant recipients, primarily due to biofilm formation. Current decontamination methods vary in efficacy, prompting interest in polymeric nanoparticles (NPs) for their antimicrobial and protein-specific cleaning properties. This study evaluated the efficacy of polymeric nanoparticles (NPs) in decontaminating titanium dental implants by removing proteinaceous pellicle layers and resisting recontamination.
View Article and Find Full Text PDFPlasma Osteoprotegerin and Cognitive Impairment after Ischemic Stroke.
Curr Neurovasc Res
January 2025
Department of Epidemiology, School of Public Health, Jiangsu Key Laboratory of Preventive and Translational Medicine for Major Chronic Non-communicable Diseases, MOE Key Laboratory of Geriatric Diseases and Immunology, Suzhou Medical College of Soochow University, Suzhou, Jiangsu Province, China.
Background: Plasma osteoprotegerin (OPG) has been linked to poor prognosis following stroke, but its impact on post-stroke cognitive impairment (PSCI) is unknown. The purpose of our work was to analyze the relationship of OPG with PSCI.
Methods: Our study included 613 ischemic stroke subjects with plasma OPG levels.
Evaluation of Safety and Efficacy of Repeated Mesenchymal Stem Cell Transplantation in Patients with Amyotrophic Lateral Sclerosis (ALS) by Investigating Patient's Specific microRNAs as Novel Biomarkers: A Clinical Trial Study.
Curr Stem Cell Res Ther
January 2025
Department of Immunology, Immunology Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Background: Since there is currently no cure for amyotrophic lateral sclerosis (ALS), it is essential to search for diagnostic biomarkers and novel treatments to reduce the severity of this disease. One of these treatment approaches is stem cell transplantation.
Objective: This study aims to evaluate the safety and efficacy of repeated transplantation of autologous bone marrow-derived mesenchymal stem cells (BM-MSCs) in patients with ALS by analyzing clinical and molecular data.
Unit-cell parameters determination from a set of independent electron diffraction zonal patterns.
Acta Crystallogr A Found Adv
March 2025
Nanostructures Research Laboratory, Japan Fine Ceramics Center, 2-4-11 Mustuno, Atsuta-ku, Nagoya, 456-8587, Japan.
Due to the short de Broglie wavelength of electrons compared with X-rays, the curvature of their Ewald sphere is low, and individual electron diffraction patterns are nearly flat in reciprocal space. As a result, a reliable unit-cell determination from a set of randomly oriented electron diffraction patterns, an essential step in serial electron diffraction, becomes a non-trivial task. Here we describe an algorithm for unit-cell determination from a set of independent electron diffraction patterns, as implemented in the program PIEP (Program for Interpreting Electron diffraction Patterns), written in the early 1990s.
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