On October 17, 1849, Poland's greatest composer, Frédéric Chopin (1810-1849) died aged 39. His cause of death remains unknown. An investigation of the documental sources was performed to reconstruct the medical history of the artist. Since his earliest years, his life had been dominated by poor health. Recurrent episodes of cough, fever, headaches, lymphadenopathy- a series of symptoms that may be attributed to viral respiratory infections- manifested in his teens. Later in life, he had chest pain, hemoptysis, hematemesis, neuralgia, and arthralgia. Exhaustion and breathlessness characterized all his adult life. Coughing, choking, and edema of the legs and ankles manifested four months before his death. Several hypotheses ranging from cystic fibrosis to alpha-1 anti-trypsin deficiency and pulmonary tuberculosis have been proposed to explain Chopin's lifelong illness. We suggest that Chopin had dilated cardiomyopathy with consequent heart failure and cirrhosis that caused his death.
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http://dx.doi.org/10.1016/j.cardfail.2018.03.009 | DOI Listing |
Dermatol Pract Concept
October 2024
Department of Geriatric - wound and healing, Rothschild Hospital, Sorbonne University, Paris, France.
Behav Sci Law
December 2024
School of Criminal Justice, University of Lausanne, Lausanne, Switzerland.
Victims of sexual homicide may be deceived by perpetrators who use a friendly approach to gain access to them, making it difficult for the victim to assess the danger posed by the stranger. When investigating sexual homicides committed by strangers, investigators often lack direct information, including how the perpetrator gained access to the victim. To identify potential predictors of the approach method used in sexual homicides, this study analyzed the preferences and behaviors of sexual murderers who target strangers based on their approach method.
View Article and Find Full Text PDFArch Womens Ment Health
December 2024
Laboratory of Human Milk and Lactation Research, Department of Medical Biology, Medical University of Warsaw, Warsaw, Poland.
Purpose: The study presents a cross-sectional analysis of the population of Ukrainian women who received maternity care in 11 Polish hospitals.
Methods: Multidirectional lactation counseling was implemented from March to November 2023 by the Human Milk Bank Foundation in cooperation with UNICEF Refugee Response Office in Poland. Medical data were collected using questionnaires prepared for the study.
Food Res Int
December 2024
Department of Biotechnology and Microbiology, Faculty of Chemistry, Gdańsk University of Technology, Narutowicza 11/12, 80-233 Gdańsk, Poland. Electronic address:
This study examined the interfacial evolution of individual bile salts (BSs) and their blends with phosphatidylcholine (BS/PC) to simulate the complex behaviour of human bile (HB) during lipolysis at the triglyceride/water interface. Using adsorption and desorption cycles, mimicking exposure to small intestinal fluids, we demonstrate that the interfacial behaviour of real HB can be replicated using simple mixtures of BSs and PC. Interfacial tension (IFT) measurements after lipolysis and desorption showed no significant differences (P > 0.
View Article and Find Full Text PDFJ Exp Med
December 2024
Section of Paediatric Infectious Disease, Department of Infectious Disease, Faculty of Medicine, Imperial College London, London, UK.
Multisystem inflammatory syndrome in children (MIS-C) is a rare condition following SARS-CoV-2 infection associated with intestinal manifestations. Genetic predisposition, including inborn errors of the OAS-RNAseL pathway, has been reported. We sequenced 154 MIS-C patients and utilized a novel statistical framework of gene burden analysis, "burdenMC," which identified an enrichment for rare predicted-deleterious variants in BTNL8 (OR = 4.
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