Particulate matter (PM) air pollution has become a serious environmental problem in Nanjing and poses great health risks to local residents. In this study, characteristics of particulate matter with an aerodynamic diameter less than 2.5 μm (PM) over Nanjing were analyzed using hourly and daily averaged PM concentrations and meteorological parameters collected from nine national monitoring sites during the period of March 2014 to February 2017. Then, the integrated exposure-response (IER) model was applied to assess premature mortality, years of life lost (YLL) attributable to PM, and mortality benefits due to PM reductions. The concentrations of PM varied among hours, seasons and years, which can be explained by differences in emission sources, secondary formations and meteorological conditions. The decreased ratio of PM to CO suggested that secondary contributions decreased while the relative contributions of vehicle exhaust increased from increased CO data. According to the values of attributable fractions (AF), stroke was the major cause of death, followed by ischemic heart disease (IHD), lung cancer (LC) and chronic obstructive pulmonary disease (COPD). The estimated total deaths in Nanjing due to PM were 12,055 and 10,771, leading to 98,802 and 87,647 years of life lost in 2014 and 2015, respectively. The elderly and males had higher health risks than youngsters and females. When the PM concentrations meet the World Health Organization (WHO) Air Quality Guidelines (AQG) of 10 μg/m³, 84% of the premature deaths would be avoided, indicating that the Nanjing government needs to adopt more stringent measure to reduce PM pollution and enhance the health benefits.
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http://dx.doi.org/10.3390/ijerph15040602 | DOI Listing |
Sci Rep
January 2025
School of Public Finance and Taxation, Southwestern University of Finance and Economics, Chengdu, 611130, China.
The influence exerted by air pollution on interregional workforce migration has garnered considerable attention in ecological economics over time; however, relatively scant consideration has been given to its effects on occupational transition dynamics. This study presents an empirical examination of the influence of air pollution on job changes among the working population and seeks to understand the underlying causal mechanisms. By merging detailed micro-level survey data with regional Fine particulate matter (PM) data from Chinese counties spanning the years 1997 to 2015, we have constructed an extensive database to support our analysis.
View Article and Find Full Text PDFEnviron Monit Assess
January 2025
Department of Agricultural Economics, College of Agriculture, Vellayani, Kerala Agricultural University, Thiruvananthapuram, Kerala, India.
This study quantified the environmental impacts of residue burning of major produced and burned crops in Madhya Pradesh, central India. The environmental impacts were quantified using Life Cycle Assessment (LCA) coupled with Monte Carlo simulation of 1000 iterations. Crop wise marginal impacts of the crops have been quantified using Multivariate regression model.
View Article and Find Full Text PDFDrug Metab Dispos
January 2025
Department of Pharmacology and Experimental Therapeutics, Louisiana State University Health Science Center, New Orleans, Louisiana; The Stanley S. Scott Cancer Center, Louisiana State University Health Science Center, New Orleans, Louisiana. Electronic address:
Environmentally persistent free radicals (EPFRs) are a recently recognized component of particulate matter that cause respiratory and cardiovascular toxicity. The mechanism of EPFR toxicity appears to be related to their ability to generate reactive oxygen species (ROS), causing oxidative damage. EPFRs were shown to affect cytochrome P450 (P450) function, inducing the expression of some forms through the Ah receptor.
View Article and Find Full Text PDFEur Respir J
January 2025
Division of Pulmonary, Allergy, Critical Care, and Sleep Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, U.S.A.
Background: The role of epigenetic aging in the environmental pathogenesis and prognosis of fibrotic interstitial lung disease (fILD) is unclear. We evaluated whether ambient particulate matter ≤2.5 μm (PM) and neighbourhood disadvantage exposures are associated with accelerated epigenetic aging, and whether epigenetic age is associated with adverse clinical outcomes in patients with fILD.
View Article and Find Full Text PDFInt Immunopharmacol
January 2025
Department of Respiratory Medicine, The First Hospital of Jilin University, Changchun 130021 China. Electronic address:
Background: Fine particulate matter (PM2.5) is a global environmental problem that threatens public health because it can induce ferroptosis and cause lung injury. Hesperetin (Hes), a natural compound widely present in fruits and vegetables, can activate nuclear factor erythroid 2-related factor 2 (Nrf2), thereby exerting powerful antioxidant effects.
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