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Risks and rates, and the mathematical link between them.
Eur J Epidemiol
January 2025
Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, QC, H3A 1G1, Canada.
The risk over a given time span can be calculated as one minus the exponentiated value of the negative of the integral of the incidence density function (or hazard rate function) over that time span. This relationship is widely used but, in the few instances where textbooks have presented it, the derivations of it tend to be purely mathematical. I first review the historical contexts, definitions, distinctions and links.
View Article and Find Full Text PDFExamining the arrhythmogenicity of dobutamine when used in conjunction with isoflurane in horses: A retrospective study at a single university teaching hospital.
Vet Rec
January 2025
Department of Clinical Sciences, Auburn University, Auburn, Alabama, USA.
Background: Dobutamine is used to treat hypotension in isoflurane-anaesthetised horses but may produce arrhythmias. Halothane is a volatile anaesthetic that was, historically, widely used in horses, but in one study, 56 of 200 halothane-anaesthetised horses (28%) developed arrhythmias after dobutamine administration. Although isoflurane has largely replaced halothane, it is unknown how isoflurane and dobutamine interact in the development of arrhythmias.
View Article and Find Full Text PDFEnsuring Medical Device Safety: The Role of Standards Organizations and Regulatory Bodies.
J Med Syst
January 2025
Advancing a Healthier Wisconsin Endowment, Medical College of Wisconsin, Milwaukee, WI, USA.
Medical devices significantly enhance healthcare by integrating advanced technology to improve patient outcomes. Ensuring their safety and reliability requires a delicate balance between innovation and rigorous oversight, managed through the collaborative efforts of standards development organizations, standards accrediting organizations, and regulatory agencies such as the U.S.
View Article and Find Full Text PDFMultiple Lurias. Reconstructing Alexander Romanovich's Life-Writing.
Integr Psychol Behav Sci
January 2025
Archives Henri Poincaré, Université de Lorraine, Nancy, France.
While widely considered Alexander Luria's (1902-1977) autobiography, The Making of Mind. A Personal Account of Soviet Psychology, published posthumously in 1979, is not a true autobiography but rather an autobiography with heterobiographic elements. However, the largely overlooked Spanish book, Mirando hacia atrás.
View Article and Find Full Text PDFIntergenerational Impacts of Historical Trauma on Contemporary Depression Symptoms Among Indigenous Communities.
J Am Acad Child Adolesc Psychiatry
January 2025
Johns Hopkins University, Duluth, Minnesota.
Introduction: Indigenous communities in the U.S. and Canada have endured generations of historical trauma.
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