Genetic Relationships among Multidrug-Resistant Salmonella enterica Serovar Typhimurium Strains from Humans and Animals.

Antimicrob Agents Chemother

Central Regional Laboratory, Center for Diagnostics and Vaccine Development, Centers for Disease Control, Ministry of Health and Welfare, Taipei, Taiwan

Published: May 2018

We identified 20 to 22 resistance genes, carried in four incompatibility groups of plasmids, in each of five genetically closely related serovar Typhimurium strains recovered from humans, pigs, and chickens. The genes conferred resistance to aminoglycosides, chloramphenicol, sulfonamides, trimethoprim, tetracycline, fluoroquinolones, extended-spectrum cephalosporins and cefoxitin, and azithromycin. This study demonstrates the transmission of multidrug-resistant strains among humans and food animals and may be the first identification of in azithromycin-resistant strains in Taiwan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923113PMC
http://dx.doi.org/10.1128/AAC.00213-18DOI Listing

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