AI Article Synopsis
- 46 clinical isolates were genetically reidentified, resulting in 27 strains of one type and 12 strains of another type.* -
- Most of the strains from the first type were isolated from blood cultures, while the second type was not.* -
- The first type was found to be more sensitive to antifungals and immune response, but both types showed susceptibility to echinocandins yet resistance to micafungin in a mouse model of invasive candidiasis.*
Article Abstract
A total of 46 clinical isolates of and were reidentified genetically, resulting in 27 and 12 strains. The majority of strains, but not strains, were isolated from blood cultures. was more sensitive to antifungals, hydrogen peroxide, and killing by murine macrophages than was The isolates were echinocandin susceptible but resistant to micafungin in a murine model of invasive candidiasis.
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Source |
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5971574 | PMC |
| http://dx.doi.org/10.1128/AAC.02528-17 | DOI Listing |
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