Aim: Our study objectives were to evaluate umbilical cord blood acid-base balance in presence of nuchal cord at delivery, effects of nuchal cord at delivery on perinatal outcomes and incidence of nuchal cord in a racially diverse population.
Methods: Perinatal records of 2530 women (predominantly African American and Hispanic) who delivered in 2012 were examined. Perinatal outcomes of women who delivered a baby with nuchal cord were compared with those without nuchal cord.
Results: In this study, incidence of nuchal cord was 23.5% and incidence of tight nuchal cord was 1.9%; 4.2% of babies with nuchal cord required resuscitation and 3.2% of babies with nuchal cord needed to be admitted to NICU. In our study, 4.2% of babies with nuchal cord required resuscitation and in total 3.2% of babies with nuchal cord needed to be admitted to NICU. Nuchal cord frequency increased from 15.6% at ≤36 weeks to 22.8% at ≥37 weeks. Significantly elevated umbilical cord Veno-Arterial pH differential was noted in babies with nuchal cord, indicating fetal acidemia.
Conclusions: Perinatal outcomes of pregnancies with nuchal cord in predominantly African American and Hispanic women were not adversely affected. Analysis of umbilical cord blood gases suggests mixed respiratory and metabolic fetal acidosis.
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http://dx.doi.org/10.1016/j.pedneo.2018.03.002 | DOI Listing |
Int J Gynaecol Obstet
December 2024
Service de Gynécologie Obstétrique, CHU Charles-Nicolle, Rouen, France.
Fetal death is defined as the spontaneous cessation of cardiac activity after 14 weeks gestational age (GA). Regarding prevention of fetal death in the general population, it is not recommended to counsel or prescribe rest, aspirin, vitamin A, vitamin D, or micronutrient supplementation; systematically look for nuchal cord during prenatal screening ultrasound; or perform systematic antepartum monitoring by cardiotocography for the sole purpose of reducing the risk of fetal death. It is recommended to offer vaccination against influenza in epidemic periods and against SARS-CoV-2.
View Article and Find Full Text PDFAnn Neurol
December 2024
The Ritchie Centre, Hudson Institute of Medical Research, Melbourne, Victoria, Australia.
Objective: Hypoxic-ischemic encephalopathy (HIE) is a major cause of perinatal brain injury. Creatine is a dietary supplement that can increase intracellular phosphocreatine to improve the provision of intracellular adenosine triphosphate (ATP) to meet the increase in metabolic demand of oxygen deprivation. Here, we assessed prophylactic fetal creatine supplementation in reducing acute asphyxia-induced seizures, disordered electroencephalography (EEG) activity and cerebral inflammation and cell death histopathology.
View Article and Find Full Text PDFJ Clin Med
November 2024
Department of Prenatal Cardiology, Polish Mother's Memorial Hospital Research Institute, 93-338 Lodz, Poland.
Better understanding of and addressing umbilical entanglement in the third trimester of pregnancy is necessary to estimate its impact on fetal circulation. An analysis of single physiological pregnancies wrapped with one or two coils of the umbilical cord around the neck makes it possible to understand the severity of the problem and distinguish it from perinatal umbilical strangulation. In an echocardiographic study performed at 32.
View Article and Find Full Text PDFInt J Gen Med
November 2024
Department of Pediatrics, Meizhou People's Hospital, Meizhou Academy of Medical Sciences, Meizhou, People's Republic of China.
Cureus
September 2024
Department of Obstetrics and Gynecology, Shiga University of Medical Science, Otsu, JPN.
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