Purpose: Cerebral palsy (CP) is the most common motor disability of childhood. Less is known about its prevalence and associated factors in Switzerland, so we aimed to fill this knowledge gap in one Swiss canton, evaluating the feasibility to build up a CP registry.
Methods: A retrospective review of medical records was undertaken. Children born during 1995 and 2009 in the canton of Saint Gallen diagnosed with CP were eligible for inclusion.
Results: A total of 140 patients formed the study cohort. The prevalence of CP was 0.19%, with 85% of children affected by spastic CP.
Conclusions: The results of the present study were comparable with data of the Surveillance of Cerebral Palsy in Europe network. Moreover, this pilot study demonstrated the feasibility and usefulness of creating a registry of children affected by CP.
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http://dx.doi.org/10.1097/PEP.0000000000000491 | DOI Listing |
BMC Pediatr
January 2025
Department of Developmental and Behavioral Pediatrics, Children's Medical Center, The First Hospital of Jilin University, Changchun, China.
Background: Most previous studies have focused on the clinical efficacy after intervention of ESDM, particularly in core symptoms. However, only a few have paid attention to the effectiveness of ESDM on emotional dysregulation and behavior problems in children with ASD. This study aimed to explore the effect of the ESDM on addressing emotional dysregulation and behavior problems in children with ASD in China, as well as its correlation with core symptoms of ASD.
View Article and Find Full Text PDFPLoS One
January 2025
Clinic for Orthopaedics, Heidelberg University Hospital, Heidelberg, Germany.
Duchenne gait, characterized by an ipsilateral trunk lean towards the affected stance limb, compensates for weak hip abductor muscles, notably the gluteus medius (GM). This study aims to investigate how electromyographic (EMG) cluster analysis of GM contributes to a better understanding of Duchenne gait in patients with cerebral palsy (CP). We analyzed retrospective gait data from 845 patients with CP and 65 typically developed individuals.
View Article and Find Full Text PDFPLoS One
January 2025
Neurorehabilitation and Biomechanics Research Section, Rehabilitation Medicine Department, Clinical Center, National Institutes of Health, Bethesda, MD, United States of America.
Children with cerebral palsy (CP) often participate in training to improve mobility, hand function and other motor abilities. However, responses to these interventions vary considerably across individuals even those with similar brain injuries, ages and functional levels. Dopamine is a neurotrasmitter known to affect motor skill acquistion in animals and humans and may be influenced by individual variations in genes related to brain transmission of dopamine.
View Article and Find Full Text PDFPediatrics
January 2025
Department of Pediatrics, University of British Columbia, Vancouver, British Columbia, Canada.
Background And Objectives: The likelihood and severity of neurodevelopmental impairment (NDI) affects critical health care decisions. NDI definitions were developed without parental perspectives. We investigated the agreement between parental vs medical classification of NDI among children born preterm.
View Article and Find Full Text PDFBackground: Microhemorrhages and superficial siderosis (SS) have been reported in patients with mild cognitive impairment (MCI) and dementia, especially in the context of Alzheimer's disease (AD) and cerebrovascular disease. Cerebral amyloid angiopathy and small vessel disease (SVD) have both been implicated in microhemorrhages and SS but their prevalence in those with MCI and dementia and their relationship to SVD is unknown.
Method: We conducted a retrospective chart review of patients with MCI or dementia that had undergone MRI scans from 2014 To 2023.
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